Evidence map›Paper›PMID 28352127›Full record

ArticleScientific reports2017

Insights from engraftable immunodeficient mouse models of hyperinsulinaemia.

Michelle L Maugham, Patrick B Thomas, Gabrielle J Crisp, Lisa K Philp, Esha T Shah, Adrian C Herington, Chen Chen, Laura S Gregory, Colleen C Nelson, Inge Seim and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. LIGHT/TNFSF14 Affects Adipose Tissue Phenotype.International journal of molecular sciences · 2024
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  9. CD4Frontiers in immunology · 2020
    Article
  10. Article
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  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Michelle L MaughamGhrelin Research Group, Translational Research Institute, Institute of Health and Biomedical Innovation, and School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.
Patrick B ThomasGhrelin Research Group, Translational Research Institute, Institute of Health and Biomedical Innovation, and School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID 0000-0002-3649-7923
Gabrielle J CrispGhrelin Research Group, Translational Research Institute, Institute of Health and Biomedical Innovation, and School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.
Lisa K PhilpGhrelin Research Group, Translational Research Institute, Institute of Health and Biomedical Innovation, and School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.
Esha T ShahGhrelin Research Group, Translational Research Institute, Institute of Health and Biomedical Innovation, and School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.
Adrian C HeringtonGhrelin Research Group, Translational Research Institute, Institute of Health and Biomedical Innovation, and School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.
Chen ChenSchool of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Queensland, Australia.
Laura S GregorySkeletal Biology and Forensic Anthropology Research Laboratory, Cancer Program, School of Biomedical Sciences, Translational Research Institute (TRI), Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
Colleen C NelsonAustralian Prostate Cancer Research Centre - Queensland, Institute of Health and Biomedical Innovation, Queensland University of Technology, Princess Alexandra Hospital, Translational Research Institute, Brisbane, Queensland, Australia.
Inge SeimGhrelin Research Group, Translational Research Institute, Institute of Health and Biomedical Innovation, and School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.
Penny L JefferyGhrelin Research Group, Translational Research Institute, Institute of Health and Biomedical Innovation, and School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia. p.jeffery@qut.edu.au.
Lisa K ChopinGhrelin Research Group, Translational Research Institute, Institute of Health and Biomedical Innovation, and School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia. l.chopin@qut.edu.au.
Translational Research Institute · AUThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperinsulinaemia, obesity and dyslipidaemia are independent and collective risk factors for many cancers. Here, the long-term effects of a 23% Western high-fat diet (HFD) in two immunodeficient mouse strains (NOD/SCID and Rag1

Indexed as

Disease Models, AnimalDisease SusceptibilityAdipose TissueAnimalsBlood GlucoseBody WeightDiet, High-FatFemaleHeterograftsHomeodomain ProteinsHumansHyperinsulinismInsulinLiverMaleMiceBlood GlucoseHomeodomain ProteinsInsulinRAG-1 protein

Identifiers

PMID28352127
PMCPMC5428450
OpenAlexW2601033398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.