Evidence map›Paper›PMID 28351964›Full record

ArticlePhysiological reports2017

Left ventricular remodeling leads to heart failure in mice with cardiac-specific overexpression of VEGF-B

Line Lottonen-Raikaslehto, Riina Rissanen, Erika Gurzeler, Mari Merentie, Jenni Huusko, Jurgen E Schneider, Timo Liimatainen, Seppo Ylä-Herttuala

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Guidelines for measuring cardiac physiology in mice.American journal of physiology. Heart and circulatory physiology · 2018
    Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Susceptibility to Cardiac Arrhythmias and Sympathetic Nerve Growth in VEGF-B Overexpressing Myocardium.Molecular therapy : the journal of the American Society of Gene Therapy · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Getting to the heart of the sphingolipid riddle.Current opinion in physiology · 2018
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Line Lottonen-RaikaslehtoDepartment of Biotechnology and Molecular Medicine, A. I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
Riina RissanenDepartment of Biotechnology and Molecular Medicine, A. I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
Erika GurzelerDepartment of Biotechnology and Molecular Medicine, A. I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
Mari MerentieDepartment of Biotechnology and Molecular Medicine, A. I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
Jenni HuuskoDepartment of Biotechnology and Molecular Medicine, A. I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
Jurgen E SchneiderRadcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, United kingdom.
Timo LiimatainenDepartment of Biotechnology and Molecular Medicine, A. I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
Seppo Ylä-HerttualaDepartment of Biotechnology and Molecular Medicine, A. I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland seppo.ylaherttuala@uef.fi.
University of Eastern Finland · FIUniversity of Oxford · GB

Funding

British Heart Foundation FS/11/50/29038
6 · The paper itself

Abstract

Cardiac-specific overexpression of vascular endothelial growth factor (VEGF)-B

Indexed as

AnimalsDisease Models, AnimalDisease ProgressionEchocardiographyElectrocardiographyHeart FailureHeart VentriclesMagnetic Resonance ImagingMaleMiceMyocardiumVascular Endothelial Growth Factor BVentricular RemodelingVascular Endothelial Growth Factor BVEGFB protein, humanCardiovascular imagingheart failureleft ventricular hypertrophymouse ECGvascular endothelial growth factor ‐B

Identifiers

PMID28351964
PMCPMC5371547
OpenAlexW2599943669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.