Evidence map›Paper›PMID 28351918›Full record

ArticlemBio2017

A Novel Mechanism for Protein Delivery by the Type 3 Secretion System for Extracellularly Secreted Proteins.

Farid Tejeda-Dominguez, Jazmin Huerta-Cantillo, Lucia Chavez-Dueñas, Fernando Navarro-Garcia

Abstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  5. Review
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  10. Article
  11. The TAL Effector AvrBs3 fromFrontiers in microbiology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Farid Tejeda-DominguezDepartment of Cell Biology, Centro de Investigación y de Estudios Avanzados del IPN (CINVESTAV-IPN), Mexico City, Mexico.
Jazmin Huerta-CantilloDepartment of Cell Biology, Centro de Investigación y de Estudios Avanzados del IPN (CINVESTAV-IPN), Mexico City, Mexico.
Lucia Chavez-DueñasDepartment of Cell Biology, Centro de Investigación y de Estudios Avanzados del IPN (CINVESTAV-IPN), Mexico City, Mexico.
Fernando Navarro-GarciaDepartment of Cell Biology, Centro de Investigación y de Estudios Avanzados del IPN (CINVESTAV-IPN), Mexico City, Mexico fnavarro@cell.cinvestav.mx.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The type 3 secretion system (T3SS) is essential for bacterial virulence through delivering effector proteins directly into the host cytosol. Here, we identified an alternative delivery mechanism of virulence factors mediated by the T3SS, which consists of the association of extracellularly secreted proteins from bacteria with the T3SS to gain access to the host cytosol. Both EspC, a protein secreted as an enteropathogenic

Indexed as

Bacterial Outer Membrane ProteinsEscherichia coliEscherichia coli ProteinsProtein TransportProtein Tyrosine PhosphatasesType III Secretion SystemsYersiniaBacterial Outer Membrane ProteinsEscherichia coli ProteinsEspC protein, E coliProtein Tyrosine PhosphatasesType III Secretion SystemsyopH protein, Yersiniaautotransporter proteinsenteropathogenic E. coliEspA filamentEspB-EspD poreEspCprotein bindingprotein translocationsecretion systemstranslocator proteinsYopH

Identifiers

PMID28351918
PMCPMC5371411

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.