Evidence map›Paper›PMID 28351916›Full record

ArticlemBio2017

Identification of MupP as a New Peptidoglycan Recycling Factor and Antibiotic Resistance Determinant in

Coralie Fumeaux, Thomas G Bernhardt

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. ACS infectious diseases · 2026
    Article
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  8. Collateral Sensitivity to Fosfomycin of Tobramycin-Resistant Mutants ofInternational journal of molecular sciences · 2023
    Article
  9. Article
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  12. Article
  13. Review
  14. Article
  15. Constructing and deconstructing the bacterial cell wall.Protein science : a publication of the Protein Society · 2020
    Review
  16. Article
  17. Chemical Reporters for Exploring Microbiology and Microbiota Mechanisms.Chembiochem : a European journal of chemical biology · 2020
    Review
  18. Article
  19. Interplay between Peptidoglycan Biology and Virulence in Gram-Negative Pathogens.Microbiology and molecular biology reviews : MMBR · 2018
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Coralie FumeauxDepartment of Microbiology and Immunobiology, Harvard Medical School, Boston, USA.
Thomas G BernhardtDepartment of Microbiology and Immunobiology, Harvard Medical School, Boston, USA thomas_bernhardt@hms.harvard.edu.
Harvard University · US

Funding

Peptidoglycan Biogenesis in Escherichia ColiR01AI083365 · NIAID · HARVARD MEDICAL SCHOOL · PI Thomas G Bernhardt · 2010 to 2026
$8.3M
Targeting cell separation systems of gram-negative bacteria.R33AI111713 · NIAID · HARVARD MEDICAL SCHOOL · PI BERNHARDT, THOMAS G · 2016 to 2018
$1.5M
NIAID NIH HHS R01 AI083365NIAID NIH HHS R33 AI111713Swiss National Science Foundation 171535
6 · The paper itself

Abstract

Peptidoglycan (PG) is an essential cross-linked polymer that surrounds most bacterial cells to prevent osmotic rupture of the cytoplasmic membrane. Its synthesis relies on penicillin-binding proteins, the targets of beta-lactam antibiotics. Many Gram-negative bacteria, including the opportunistic pathogen

Indexed as

Drug Resistance, BacterialCell WallDNA Transposable ElementsMutagenesis, InsertionalPeptidoglycanPhosphoric Monoester HydrolasesPseudomonas aeruginosaDNA Transposable ElementsPeptidoglycanPhosphoric Monoester Hydrolases

Identifiers

PMID28351916
PMCPMC5371409
OpenAlexW2601280329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.