Evidence map›Paper›PMID 28351846›Full record

ArticlePediatrics2017

Postural Heart Rate Changes in Young Patients With Vasovagal Syncope.

Marvin S Medow, Sana Merchant, Melissa Suggs, Courtney Terilli, Breige O'Donnell-Smith, Julian M Stewart

Open access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Sinus Tachycardia: a Multidisciplinary Expert Focused Review.Circulation. Arrhythmia and electrophysiology · 2022
    Review
  3. Diagnosis and management of postural orthostatic tachycardia syndrome.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marvin S MedowDepartments of Pediatrics, and marvin_medow@nymc.edu.
Sana MerchantDepartments of Pediatrics, and.
Melissa SuggsDepartments of Pediatrics, and.
Courtney TerilliDepartments of Pediatrics, and.
Breige O'Donnell-SmithDepartments of Pediatrics, and.
Julian M StewartDepartments of Pediatrics, and.
Pediatrics and Genetics · USNew York Medical College · US

Funding

Local Vasoconstriction in Postural Tachycardia SyndromeR01HL074873 · NHLBI · NEW YORK MEDICAL COLLEGE · PI STEWART, JULIAN M · 2004 to 2013
$3.4M
Mechanisms of Vasovagal SyncopeR01HL112736 · NHLBI · NEW YORK MEDICAL COLLEGE · PI STEWART, JULIAN M · 2013 to 2016
$2.1M
Reducing Orthostatic Intolerance with Oral Rehydration in Patients with Myalgic Encephalomyelitis/Chronic Fatigue SyndromeR21NS094644 · NINDS · NEW YORK MEDICAL COLLEGE · PI MEDOW, MARVIN S · 2016 to 2017
$451k
NHLBI NIH HHS R01 HL074873NHLBI NIH HHS R01 HL112736NINDS NIH HHS R21 NS094644
6 · The paper itself

Abstract

BACKGROUND AND

objectivesRecurrent postural vasovagal syncope (VVS) is caused by transient cerebral hypoperfusion from episodic hypotension and bradycardia; diagnosis is made by medical history. VVS contrasts with postural tachycardia syndrome (POTS), defined by chronic daily symptoms of orthostatic intolerance with excessive upright tachycardia without hypotension. POTS has recently been conflated with VVS when excessive tachycardia is succeeded by hypotension during tilt testing. We hypothesize that excessive tachycardia preceding hypotension and bradycardia is part of the vasovagal response during tilt testing of patients with VVS.

methodsWe prospectively performed head-up tilt (HUT) testing on patients with recurrent VVS (

resultsBaseline parameters were the same in both groups. HR (supine versus 5 and 10 minutes HUT) significantly increased in control (65 ± 2.6 vs 83 ± 3.6 vs 85 ± 3.7,

conclusionsOrthostasis in VVS is accompanied by large increases in HR that should not be construed as POTS.

Indexed as

AdolescentBlood PressureChildFemaleHeart RateHumansMaleOrthostatic IntoleranceProspective StudiesSyncope, VasovagalTilt-Table TestYoung Adult

Identifiers

PMID28351846
PMCPMC5369676
OpenAlexW2602505693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.