ReviewArchives of disease in childhood2017
Cutaneous manifestations of tuberous sclerosis complex and the paediatrician's role.
Review in Archives of disease in childhood, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Minor Physical Anomalies and Congenital Malformations Among Children with Psychotic Symptoms: An Exploratory Descriptive Study with Illustrative Clinical Cases.Brain sciences · 2026Article
- Ten-year follow-up of monozygotic twin sisters with TSC-LAM: A rare case report.Respiratory medicine case reports · 2026Article
- Renal Angiomyolipoma in a Young Woman With Tuberous Sclerosis: A Case Report.Clinical case reports · 2026Article
- Review of the spectrum of tuberous sclerosis complex: The Saudi Arabian Experience.Neurosciences (Riyadh, Saudi Arabia) · 2024Article
- Neurocutaneous Diseases: Diagnosis, Management, and Treatment.Journal of clinical medicine · 2024Review
- Tuberous Sclerosis Complex Presenting as Periungual Fibromas: A Rare Case Report and Literature Review.Clinical, cosmetic and investigational dermatology · 2024Article
- Neurological and Dermatological Manifestations of Tuberous Sclerosis Complex: Report from a Romanian Tertiary Hospital Cohort.Journal of clinical medicine · 2023Article
- Late diagnosis of tuberous sclerosis: a case report.Oxford medical case reports · 2023Article
- Uterine collision tumor (PEComa and endometrioid carcinoma) in a tuberous sclerosis patient: a case report.Frontiers in oncology · 2023Article
- Giant Koenen Tumors as the Presenting and Only Clinical Sign of Tuberous Sclerosis Complex in a 56-Year-Old Man and Its Surgical Management.Skin appendage disorders · 2022Article
- Tuberous sclerosis complex with skin lesions as the initial presentation: A case report and multidisciplinary discussion.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022Article
- Analysis of Clinical Features and Next-Generation Sequencing of 12 Tuberous Sclerosis Families in China.Frontiers in medicine · 2022Article
- Diagnostic features of tuberous sclerosis complex: case report and literature review.Quantitative imaging in medicine and surgery · 2022Article
- An unusual case of multiple bilateral kidney tumors.Journal of nephrology · 2021Article
- Cutaneous Expression of Familial Cancer Syndromes.Acta dermato-venereologica · 2021Review
- Birt-Hogg-Dubé syndrome-associated renal cell carcinoma: Histopathological features and diagnostic conundrum.Cancer science · 2020Review
- A step-wise approach for establishing a multidisciplinary team for the management of tuberous sclerosis complex: a Delphi consensus report.Orphanet journal of rare diseases · 2019Article
- Comparison Between Size and Stage of Preoperative Tumor Defined by Preoperative Magnetic Resonance Imaging and Postoperative Specimens After Radical Resection of Esophageal Cancer.Technology in cancer research & treatment · 2019Article
- Update on Genetic Conditions Affecting the Skin and the Kidneys.Frontiers in pediatrics · 2018Review
- Rapamycin therapy for neonatal tuberous sclerosis complex with cardiac rhabdomyomas: A case report and review.Experimental and therapeutic medicine · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tuberous sclerosis complex (TSC) is a multisystem genetic disorder stemming from unregulated activation of the mammalian target of rapamycin (mTOR) pathway, resulting in the growth of hamartomas in multiple organs. TSC-related skin lesions often develop early in life and can be disfiguring, emotionally distressful and even painful at times. Recognition of TSC-associated skin features by paediatricians can be a catalyst for facilitating early implementation of treatment strategies and establishing appropriate follow-up care. The range of potential treatment options for symptomatic or disfiguring TSC-associated skin lesions includes non-pharmacological (surgical excision, laser therapy) and pharmacological (eg, topical or systemic mTOR inhibitors) alternatives. In this review, we discuss the relevance of TSC-associated skin findings, highlight available treatment options, review guideline recommendations and emphasise the role of the primary care physician in the management of this complex disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.