Evidence map›Paper›PMID 28351407›Full record

Trial reportReproductive health2017

Maternal fat free mass during pregnancy is associated with birth weight.

Yanxia Wang, Jie Mao, Wenling Wang, Jie Qiou, Lan Yang, Simin Chen

Expression of concernOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Reproductive health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 51 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Glucose metabolism in gestational diabetes and their relationship with fat mass / muscle mass index.European journal of obstetrics & gynecology and reproductive biology: X · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. The Changing Climate and Pregnancy Health.Current environmental health reports · 2022
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Observational
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yanxia WangInstitute of Maternity and Child-Care Research, Gansu Provincial Maternity and Child-care Hospital, No.143.Qilihe north Rd., Lanzhou, Gansu, 730030, People's Republic of China. evawyx@163.com.
Jie MaoDepartment of Nutrition, Lanzhou University the Second hospital, Lanzhou, Gansu, China.
Wenling WangInstitute of Maternity and Child-Care Research, Gansu Provincial Maternity and Child-care Hospital, No.143.Qilihe north Rd., Lanzhou, Gansu, 730030, People's Republic of China.
Jie QiouInstitute of Maternity and Child-Care Research, Gansu Provincial Maternity and Child-care Hospital, No.143.Qilihe north Rd., Lanzhou, Gansu, 730030, People's Republic of China.
Lan YangInstitute of Maternity and Child-Care Research, Gansu Provincial Maternity and Child-care Hospital, No.143.Qilihe north Rd., Lanzhou, Gansu, 730030, People's Republic of China.
Simin ChenDepartment of Nutrition, Lanzhou University the Second hospital, Lanzhou, Gansu, China.
Gansu Provincial Maternal and Child Health Hospital · CNLanzhou University Second Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between maternal body compositions and birth weight was not definite. Fat Mass (FM) and Fat Free Mass (FFM) can accurately reflect the maternal body fat compositions and have been considered as better predictors of birth weight. Despite its potential role, no studies have been described the maternal compositions during pregnancy in East Asian women previously. We investigated the correlation between birth weight and Maternal body composition including fat mass (FM) and fat free mass (FFM). To determine whether birth weight is associated with maternal body fat FM and FFM during pregnancy and, if so, which trimester and parameter is more critical in determining birth weight.

methodsA longitudinal prospective observational study performed, 348, 481 and 321 non-diabetics Han Chinese women with a singleton live birth attending a routine visit in their first, second and third trimesters were recruited. Maternal body composition was measured using segmental multi-frequency bioelectrical impedance analysis. Data of the pre-pregnancy body mass index (BMI), maternal BMI, the gestational weight gain (GWG), and placental and birth weight were collected.

resultsA significant correlation exists between maternal FFM in the process of pregnancy, placental weight, GWG at delivery, and birth weight (P < 0.05). On stepwise multiple linear regression analysis, material's FFM was the most important factor associated with the birth weight. After adjustment, there was significantly associated with 2.47-fold increase in risk for birth weight more than 4 kg when FFM ≥ 40.76 kg (Upper quartile of participants). The increased maternal age became a protective factor (OR = 0.69) while the increased pre-pregnancy BMI (OR = 1.50) remained predictors to birth weight more than 4 kg.

conclusionsThe change of maternal FFM during pregnancy is independently affected the birth weight.

Indexed as

AdiposityBirth WeightBody CompositionMaternal AgeMuscle DevelopmentAdultBody Mass IndexFemaleHumansInfant, NewbornLongitudinal StudiesPregnancyProspective StudiesYoung AdultBirth weightFat free massFat massMaternal body composition

Identifiers

PMID28351407
PMCPMC5371275
OpenAlexW2598433715

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.