SynthesisBMC cancer2017
Follicular thyroid carcinoma metastasis to the facial skeleton: a systematic review.
Synthesis in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- False-positive and true-positive orbital iodine-131 uptake after radioiodine therapy: two contrasting cases clarified by SPECT/CT.Quantitative imaging in medicine and surgery · 2026Article
- Article
- Occult Papillary Carcinoma Thyroid with Solitary Appendicular Bone Metastasis in Proximal Humerus - A Case Report.Journal of orthopaedic case reports · 2025Article
- Ectopic thyroid follicular carcinoma in the right mandible: a case report.Gland surgery · 2024Article
- Metastatic thyroid follicular carcinoma presenting as pathological left clavicle fracture: An unusual skeletal metastasis at the time of diagnosis.International journal of surgery case reports · 2024Article
- Agrin is a novel oncogenic protein in thyroid cancer.Oncology letters · 2023Article
- Metastatic Follicular Thyroid Carcinoma of the Mandible: A Case Report at Tertiary Care Rural Centre.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Incidence and Predictors of Synchronous Bone Metastasis in Newly Diagnosed Differentiated Thyroid Cancer: A Real-World Population-Based Study.Frontiers in surgery · 2022Article
- Modulatory role of miRNAs in thyroid and breast cancer progression and insights into their therapeutic manipulation.Current research in pharmacology and drug discovery · 2022Review
- Histopathological Spectrum of Non-Neoplastic and Neoplastic Lesions of Thyroid: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2020Article
- Etiopathogenesis of Trismus in Patients With Head and Neck Cancer: An Exploratory Literature Review.Craniomaxillofacial trauma & reconstruction · 2020Review
- Lenvatininb as Treatment for Naïve Patients with Aggressive Thyroid Cancer Bone Metastases and Bad Performance Status.Case reports in oncological medicine · 2020Article
- Distant metastasis of follicular thyroid carcinoma to the mandible: a rare case report.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2019Article
- Metastatic papillary thyroid carcinoma of the mandible: Case report and literature review.Journal of oral and maxillofacial pathology : JOMFP · 2019Article
- Fracture after radiation therapy for femoral metastasis: incidence, timing and clinical features.Journal of radiation research · 2017Article
- Follicular Thyroid Carcinoma with Unusual Mandible Metastasis.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
- Mandibular metastasis of follicular thyroid carcinoma: A case report along with the concise review of literature.Journal of oral and maxillofacial pathology : JOMFPArticle
- Orbital metastases as the initial clinical manifestation of thyroid carcinoma: A case series.Oman journal of ophthalmologyArticle
- Rare Presentation of Mandibular Metastases from Differentiated Thyroid Carcinoma: A Case Series - Experience from a Single Tertiary Care Hospital.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
- Solitary metastatic deposit in the mandible from follicular thyroid carcinoma.World journal of nuclear medicineArticle
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFollicular thyroid carcinoma (FTC) metastasis to the facial skeleton is exceedingly rare. A case of FTC metastasizing to the mandible is presented and a systematic review of the literature describing thyroid metastasis to the facial skeleton is performed. CASE PRESENTATION: A 73-year-old female presented with metastatic FTC to the mandible and underwent total thyroidectomy, segmental mandibulectomy, bone impacted fibular free flap reconstruction, and adjuvant radioactive iodine treatment. The PubMed database was searched for literature describing thyroid cancer with facial skeleton metastasis using the key words "thyroid," "cancer," "carcinoma," "metastasis," and "malignancy" with "oral cavity," "maxilla," "mandible," "sinus," "paranasal," and "orbit." Reports that only involved the soft tissues were excluded. Systematic review revealed 59 cases of well-differentiated thyroid cancer with facial skeleton metastasis: 35 mandibular metastases (21 = FTC), 6 maxilla metastases (2 = FTC), 9 orbital metastases (4 = FTC), and 11 paranasal sinus metastases (7 = FTC). Treatment included surgery, RAI, external beam radiotherapy (XRT), or a combination of these modalities. The one, two, and five-year survival rates were 100%, 79%, and 16%, respectively.
conclusionFacial skeleton metastasis of FTC is a rare clinical challenge. Optimal treatment appears to include total thyroidectomy and resection of involved structures with or without adjuvant treatment.
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