Evidence map›Paper›PMID 28350982›Full record

ArticleDevelopmental cell2017

MicroRNAs Make a Difference in Cardiovascular Robustness.

Rachael Bakker, Richard W Carthew

Abstract readComment
In one paragraph

Article in Developmental cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Molecular Filters for Noise Reduction.Biophysical journal · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Rachael BakkerDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.
Richard W CarthewDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA; Department of Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL 60611, USA. Electronic address: r-carthew@northwestern.edu.

Funding

Non-coding RNAs and their mechanisms and functions-RenewalR35GM118144 · NIGMS · NORTHWESTERN UNIVERSITY · PI Richard W. CARTHEW · 2016 to 2026
$6.8M
TRAINING PROGRAM IN ONCOGENESIS &DEVELOPMENT BIOLOGYT32CA080621 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI EKLUND, ELIZABETH ANN · 2001 to 2018
$4.1M
A systems-level study of signaling networks and differentiationR01EY025957 · NEI · UNIVERSITY OF CHICAGO · PI CARTHEW, RICHARD W., DINNER, AARON · 2016 to 2018
$1.5M
NCI NIH HHS T32 CA080621NEI NIH HHS R01 EY025957NIGMS NIH HHS R35 GM118144
6 · The paper itself

Abstract

Invertebrate microRNAs (miRNAs) can suppress developmental variability that is caused by environmental and genetic variation. In this issue of Developmental Cell, Kasper et al. (2017) show that zebrafish miRNAs suppress variability in cardiovascular development during embryogenesis, providing insight into the conserved link between miRNAs and robustness.

Indexed as

AnimalsGene Expression Regulation, DevelopmentalHumansMicroRNAsZebrafishMicroRNAs

Identifiers

PMID28350982
PMCPMC5831320

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.