Evidence map›Paper›PMID 28350903›Full record

ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2017

Advancing Diagnostics to Address Antibacterial Resistance: The Diagnostics and Devices Committee of the Antibacterial Resistance Leadership Group.

Ephraim L Tsalik, Elizabeth Petzold, Barry N Kreiswirth, Robert A Bonomo, Ritu Banerjee, Ebbing Lautenbach, Scott R Evans, Kimberly E Hanson, Jeffrey D Klausner, Robin Patel and 2 more

Abstract readReview
In one paragraph

Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Review
  3. Priorities and Progress in Diagnostic Research by the Antibacterial Resistance Leadership Group.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. The Antibacterial Resistance Leadership Group: First Steps.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Article
  14. The Antibacterial Resistance Leadership Group: Progress Report and Work in Progress.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Article
  15. The Role of Stewardship in Addressing Antibacterial Resistance: Stewardship and Infection Control Committee of the Antibacterial Resistance Leadership Group.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Review
  16. Fundamentals and Catalytic Innovation: The Statistical and Data Management Center of the Antibacterial Resistance Leadership Group.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ephraim L TsalikDivision of Infectious Diseases, Department of Medicine, Duke University Medical Center, and.
Elizabeth PetzoldDivision of Infectious Diseases, Department of Medicine, Duke University Medical Center, and.
Barry N KreiswirthPublic Health Research Institute Tuberculosis Center, New Jersey Medical School-Rutgers University, Newark.
Robert A BonomoDepartment of Medicine, Case Western Reserve University School of Medicine, and.
Ritu BanerjeeDivision of Pediatric Infectious Diseases, Vanderbilt University, Nashville, Tennessee.
Ebbing LautenbachDepartment of Medicine, Division of Infectious Diseases, the University of Pennsylvania School of Medicine, Philadelphia.
Scott R EvansCenter for Biostatistics in AIDS Research and the Department of Biostatistics, Harvard University, Boston, Massachusetts.
Kimberly E HansonDepartments of Medicine and Pathology, Divisions of Infectious Diseases and Clinical Microbiology, University of Utah, Salt Lake City.
Jeffrey D KlausnerUCLA David Geffen School of Medicine and Fielding School of Public Health, Los Angeles, California.
Robin PatelDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, Minnesota.
and the Diagnostics and Devices Committee
of the Antibacterial Resistance Leadership Group

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
NIAID NIH HHS UM1 AI104681
6 · The paper itself

Abstract

Diagnostics are a cornerstone of the practice of infectious diseases. However, various limitations frequently lead to unmet clinical needs. In most other domains, diagnostics focus on narrowly defined questions, provide readily interpretable answers, and use true gold standards for development. In contrast, infectious diseases diagnostics must contend with scores of potential pathogens, dozens of clinical syndromes, emerging pathogens, rapid evolution of existing pathogens and their associated resistance mechanisms, and the absence of gold standards in many situations. In spite of these challenges, the importance and value of diagnostics cannot be underestimated. Therefore, the Antibacterial Resistance Leadership Group has identified diagnostics as 1 of 4 major areas of emphasis. Herein, we provide an overview of that development, highlighting several examples where innovation in study design, content, and execution is advancing the field of infectious diseases diagnostics.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsBacterial InfectionsBiological Specimen BanksClinical Studies as TopicHost-Pathogen InteractionsHumansLaboratoriesLeadershipMolecular Diagnostic TechniquesProfessional Staff CommitteesResearch DesignSepsisAnti-Bacterial Agentsantibacterial resistancedevices.diagnostics

Identifiers

PMID28350903
PMCPMC5848376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.