Evidence map›Paper›PMID 28350879›Full record

Observational studyPloS one2017

Maternal psychological responses during pregnancy after ultrasonographic detection of structural fetal anomalies: A prospective longitudinal observational study.

Anne Kaasen, Anne Helbig, Ulrik F Malt, Tormod Næs, Hans Skari, Guttorm Haugen

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06302010 (The Effect of Stress Ball Intervention During Non-Stress Test on Anxiety and Fetal Well-Being in Women With High-risk Pregnancy), which is not on this map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06302010 narecruitingnot on this mapstarted 2024, after this paper: background citation

The Effect of Stress Ball Intervention During Non-Stress Test on Anxiety and Fetal Well-Being in Women With High-risk Pregnancy: A Randomized Controlled Study

TypeinterventionalSponsorHümeyra TÜLEK DENİZRan2024 to 2025Enrolled86ConditionsAnxiety, Fetal Conditions, Pregnancy RelatedArmsStress Ball Intervention
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Psychological Support in Prenatal Diagnosis: The Parental Perspective.Journal of clinical psychology in medical settings · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Mental health in pregnancy complicated by fetal anomaly: depression screening and referrals in a single fetal care center.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Prenatal diagnosis of orofacial clefts: unveiling the parents' experience.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Anne KaasenDepartment of Nursing and Health Promotion, Oslo and Akershus University College of Applied Sciences, Oslo, Norway.
Anne HelbigDepartment of Obstetrics, Oslo University Hospital, Oslo, Norway.
Ulrik F MaltDepartment of Research and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.
Tormod NæsNofima Food Research, Ås, Norway.
Hans SkariDepartment of Gastrointestinal- and Pediatric Surgery, Oslo University Hospital, Oslo, Norway.
Guttorm HaugenDepartment of Obstetrics, Oslo University Hospital, Oslo, Norway.
Oslo University Hospital · NOUniversity of Oslo · NONofima · NOOsloMet – Oslo Metropolitan University · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this longitudinal prospective observational study performed at a tertiary perinatal referral centre, we aimed to assess maternal distress in pregnancy in women with ultrasound findings of fetal anomaly and compare this with distress in pregnant women with normal ultrasound findings. Pregnant women with a structural fetal anomaly (n = 48) and normal ultrasound (n = 105) were included. We administered self-report questionnaires (General Health Questionnaire-28, Impact of Event Scale-22 [IES], and Edinburgh Postnatal Depression Scale) a few days following ultrasound detection of a fetal anomaly or a normal ultrasound (T1), 3 weeks post-ultrasound (T2), and at 30 (T3) and 36 weeks gestation (T4). Social dysfunction, health perception, and psychological distress (intrusion, avoidance, arousal, anxiety, and depression) were the main outcome measures. The median gestational age at T1 was 20 and 19 weeks in the group with and without fetal anomaly, respectively. In the fetal anomaly group, all psychological distress scores were highest at T1. In the group with a normal scan, distress scores were stable throughout pregnancy. At all assessments, the fetal anomaly group scored significantly higher (especially on depression-related questions) compared to the normal scan group, except on the IES Intrusion and Arousal subscales at T4, although with large individual differences. In conclusion, women with a known fetal anomaly initially had high stress scores, which gradually decreased, resembling those in women with a normal pregnancy. Psychological stress levels were stable and low during the latter half of gestation in women with a normal pregnancy.

Indexed as

AdultAnxietyDepressionFemaleFetal DiseasesFetusHumansLongitudinal StudiesPregnancyPregnancy ComplicationsProspective StudiesPsychometricsStress, PsychologicalSurveys and QuestionnairesUltrasonography, PrenatalYoung Adult

Identifiers

PMID28350879
PMCPMC5369773
OpenAlexW2601959099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.