Evidence map›Paper›PMID 28350805›Full record

SynthesisPloS one2017

Enhanced recovery after surgery protocol in oesophageal cancer surgery: Systematic review and meta-analysis.

Magdalena Pisarska, Piotr Małczak, Piotr Major, Michał Wysocki, Andrzej Budzyński, Michał Pędziwiatr

Abstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
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  3. [Enhanced recovery after surgery-Does the ERAS concept keep its promises].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
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  8. Trial
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  14. Cost burden following esophagectomy: A single centre observational study.World journal of gastrointestinal surgery · 2024
    Article
  15. Article
  16. Article
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  18. Review
  19. Principles of enhanced recovery in gastrointestinal surgery.Langenbeck's archives of surgery · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Magdalena Pisarska2nd Department of General Surgery, Jagiellonian University Medical College, Krakow, Poland.
Piotr Małczak2nd Department of General Surgery, Jagiellonian University Medical College, Krakow, Poland.
Piotr Major2nd Department of General Surgery, Jagiellonian University Medical College, Krakow, Poland.
Michał Wysocki2nd Department of General Surgery, Jagiellonian University Medical College, Krakow, Poland.
Andrzej Budzyński2nd Department of General Surgery, Jagiellonian University Medical College, Krakow, Poland.
Michał Pędziwiatr2nd Department of General Surgery, Jagiellonian University Medical College, Krakow, Poland.ORCID http://orcid.org/0000-0001-9073-2667

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnhanced Recovery After Surgery (ERAS) protocol are well established in many surgical disciplines, leading to decrease in morbidity and length of hospital stay. These multi-modal protocols have been also introduced to oesophageal cancer surgery. This review aimed to evaluate current literature on ERAS in oesophageal cancer surgery and conduct a meta-analysis on primary and secondary outcomes.

methodsMEDLINE, Embase, Scopus and Cochrane Library were searched for eligible studies. We analyzed data up to May 2016. Eligible studies had to contain four described ERAS protocol elements. The primary outcome was overall morbidity. Secondary outcomes included length of hospital stay, specific complications, mortality and readmissions. Random effect meta-analyses were undertaken.

resultsInitial search yielded 1,064 articles. Thorough evaluation resulted in 13 eligible articles which were analyzed. A total of 2,042 patients were included in the analysis (1,058 ERAS group and 984 treated with traditional protocols). Analysis of overall morbidity as well as complication rate did not show any significant reduction. Non-surgical complications and pulmonary complications were significantly lower in the ERAS group, RR = 0.71 95% CI 0.62-0.80, p < 0.00001 and RR = 0.75, 95% CI 0.60-0.94, p = 0.01, respectively. Meta-analysis on length of stay presented significant reduction Mean difference = -3.55, 95% CI -4.41 to -2.69, p for effect<0.00001.

conclusionsThis systematic review with a meta-analysis on ERAS in oesophageal surgery indicates a reduction of non-surgical complications and no negative influence on overall morbidity. Moreover, a reduction in the length of hospital stay was presented.

Indexed as

Esophageal NeoplasmsEsophagusHumansLength of StayPostoperative ComplicationsRecovery of FunctionSystematic Reviews as TopicTreatment Outcome

Identifiers

PMID28350805
PMCPMC5370110

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.