Evidence map›Paper›PMID 28350586›Full record

ArticleSpine2017

Predictors of Outcome in Conservative and Minimally Invasive Surgical Management of Pain Originating From the Sacroiliac Joint: A Pooled Analysis.

Julius Dengler, Bradley Duhon, Peter Whang, Clay Frank, John Glaser, Bengt Sturesson, Steven Garfin, Daniel Cher, Aaron Rendahl, David Polly and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Spine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Guideline
  2. Utility of minimally invasive percutaneous arthrodesis of the sacroiliac joint for the treatment of low back pain: systematic review of the literature.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. A retrospective cohort review of BMI on SI joint fusion outcomes: examining the evidence to improve insurance guidelines.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Advances in Pain Medicine: a Review of New Technologies.Current pain and headache reports · 2022
    Review
  16. Article
  17. Minimally Invasive Sacroiliac Fusion-a Review.Current pain and headache reports · 2022
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 3 countries.

Julius DenglerDepartment of Neurosurgery, Charité, Berlin, Germany.
Bradley DuhonDepartment of Neurosurgery, University of Colorado, Aurora, CO.
Peter WhangDepartment of Orthopedics, Yale University, New Haven, CT.
Clay FrankIntegrated Spine Care, Wawautosa, WI.
John GlaserDepartment of Orthopedic Surgery, Medical University of South Carolina, Charleston, SC.
Bengt SturessonDepartment of Orthopedics, Aleris, Ängelholm Hospital, Ängelholm, Sweden.
Steven GarfinDepartment of Orthopedics, University of California San Diego, San Diego, CA.
Daniel CherClinical Affairs, SI-BONE, San Jose, CA.
Aaron RendahlSchool of Statistics, University of Minnesota, Minneapolis, MN.
David PollyDepartments of Orthopedics and Neurosurgery, University of Minnesota, Minneapolis, MN.
INSITE, iMIA, SIFI study groups
Charité - Universitätsmedizin Berlin · DEHässleholms Sjukhus · SEMedical University of South Carolina · USUniversity of California, San Diego · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Colorado Denver · USUniversity of Minnesota · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

STUDY

designA pooled patient-level analysis of two multicenter randomized controlled trials and one multicenter single-arm prospective trial.

objectiveThe aim of this study was to identify predictors of outcome of conservative and minimally invasive surgical management of pain originating from the sacroiliac joint (SIJ). SUMMARY OF BACKGROUND DATA: Three recently published prospective trials have shown that minimally invasive SIJ fusion (SIJF) using triangular titanium implants produces better outcomes than conservative management for patients with pain originating from the SIJ. Due to limitations in individual trial sample size, analyses of predictors of treatment outcome were not conducted.

methodsWe pooled individual patient data from the three trials and used random effects models with multivariate regression analysis to identify predictors for treatment outcome separately for conservative and minimally invasive surgical treatment. Outcome was measured using visual analogue scale (VAS), Oswestry Disability Index (ODI), and EuroQOL-5D (EQ-5D).

resultsWe included 423 patients assigned to either nonsurgical management (NSM, n = 97) or SIJF (n = 326) between 2013 and 2015. The reduction in SIJ pain was 37.9 points larger [95% confidence interval (95% CI) 32.5-43.4, P < 0.0001] in the SIJF group than in the NSM group. Similarly, the improvement in ODI was 18.3 points larger (95% CI 14.3-22.4), P < 0.0001). In NSM, we found no predictors of outcome. In SIJF, a reduced improvement in outcome was predicted by smoking (P = 0.030), opioid use (P = 0.017), lower patient age (P = 0.008), and lower duration of SIJ pain (P = 0.028).

conclusionsOur results support the view that SIJF leads to better treatment outcome than conservative management of SIJ pain and that a higher margin of improvement can be predicted in nonsmokers, nonopioid users, and patients of increased age and with longer pain duration. LEVEL OF EVIDENCE: 1.

Indexed as

AdultAgedArthralgiaBack PainConservative TreatmentFemaleHumansMaleMiddle AgedMinimally Invasive Surgical ProceduresPain ManagementPredictive Value of TestsProspective StudiesRandomized Controlled Trials as TopicSacroiliac JointSpinal Fusion

Identifiers

PMID28350586
PMCPMC5636200
OpenAlexW2599100439

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.