Evidence map›Paper›PMID 28350578›Full record

Trial reportAIDS (London, England)2017

Increasing voluntary medical male circumcision uptake among adult men in Tanzania.

Mwita Wambura, Hally Mahler, Jonathan M Grund, Natasha Larke, Gerry Mshana, Evodius Kuringe, Marya Plotkin, Gissenge Lija, Maende Makokha, Fern Terris-Prestholt and 4 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Mwita WamburaaNational Institute for Medical Research, Mwanza bJhpiego, Dar es Salaam, Tanzania cCenters for Disease Control and Prevention, Atlanta, Georgia, USA dMRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, London, UK eNational AIDS Control Programme, Ministry of Health, Community Development, Gender, Elderly, and Children, Dar es Salaam, Tanzania fFaculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.
Hally Mahler
Jonathan M Grund
Natasha Larke
Gerry Mshana
Evodius Kuringe
Marya Plotkin
Gissenge Lija
Maende Makokha
Fern Terris-Prestholt
Richard J Hayes
John Changalucha
Helen A Weiss
VMMC-Tanzania Study Group
Creative Commons · USLondon School of Hygiene & Tropical Medicine · GB

Funding

Medical Research Council G0700837Medical Research Council MR/K012126/1PEPFAR
6 · The paper itself

Abstract

objectiveWe evaluated a demand-creation intervention to increase voluntary medical male circumcision (VMMC) uptake among men aged 20-34 years in Tanzania, to maximise short-term impact on HIV incidence.

methodsA cluster randomized controlled trial stratified by region was conducted in 20 outreach sites in Njombe and Tabora regions. The sites were randomized 1 : 1 to receive either a demand-creation intervention package in addition to standard VMMC outreach, or standard VMMC outreach alone. The intervention package included enhanced public address messages, peer promotion by recently circumcised men, facility setup to increase privacy, and engagement of female partners in demand creation. The primary outcome was the proportion of VMMC clients aged 20-34 years.

findingsOverall, 6251 and 3968 VMMC clients were enrolled in intervention and control clusters, respectively. The proportion of clients aged 20-34 years was slightly greater in the intervention than control arm [17.7 vs. 13.0%; prevalence ratio = 1.36; 95% confidence intervals (CI):0.9-2.0]. In Njombe region, the proportion of clients aged 20-34 years was similar between arms but a significant two-fold difference was seen in Tabora region (P value for effect modification = 0.006). The mean number of men aged 20-34 years (mean difference per cluster = 97; 95% CI:40-154), and of all ages (mean difference per cluster = 227, 95% CI:33-420) were greater in the intervention than control arm.

conclusionThe intervention was associated with a significant increase in the proportion of clients aged 20-34 years in Tabora but not in Njombe. The intervention may be sensitive to regional factors in VMMC programme scale-up, including saturation.

Indexed as

Attitude to HealthAdultBehavior TherapyCircumcision, MaleHumansMaleSexually Transmitted DiseasesTanzaniaYoung Adult

Identifiers

PMID28350578
PMCPMC5378002
OpenAlexW2601221844

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.