Evidence map›Paper›PMID 28350443›Full record

ArticleJournal of the American Chemical Society2017

Monitoring the Disassembly of Virus-like Particles by

Rogen L C Leung, Matthew D M Robinson, Alaa A A Ajabali, Gogulan Karunanithy, Brian Lyons, Ritu Raj, Saeed Raoufmoghaddam, Shabaz Mohammed, Timothy D W Claridge, Andrew J Baldwin and 1 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Incorporation of the Trifluoromethylthio Group (CFThe Journal of organic chemistry · 2026
    Review
  2. Article
  3. Virus-Glycan Interactions Studied by Solute NMR.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  4. Virus-like Particles: Fundamentals and Biomedical Applications.International journal of molecular sciences · 2022
    Review
  5. Article
  6. Review
  7. Article
  8. Perfluorocarbons in Chemical Biology.Chembiochem : a European journal of chemical biology · 2020
    Review
  9. Article
  10. Selective Radical Trifluoromethylation of Native Residues in Proteins.Journal of the American Chemical Society · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rogen L C LeungChemistry Research Laboratory, Department of Chemistry, University of Oxford , Mansfield Road, Oxford OX1 3TA, United Kingdom.
Matthew D M RobinsonChemistry Research Laboratory, Department of Chemistry, University of Oxford , Mansfield Road, Oxford OX1 3TA, United Kingdom.
Alaa A A AjabaliChemistry Research Laboratory, Department of Chemistry, University of Oxford , Mansfield Road, Oxford OX1 3TA, United Kingdom.
Gogulan KarunanithyChemistry Research Laboratory, Department of Chemistry, University of Oxford , Mansfield Road, Oxford OX1 3TA, United Kingdom.
Brian LyonsChemistry Research Laboratory, Department of Chemistry, University of Oxford , Mansfield Road, Oxford OX1 3TA, United Kingdom.
Ritu RajChemistry Research Laboratory, Department of Chemistry, University of Oxford , Mansfield Road, Oxford OX1 3TA, United Kingdom.
Saeed RaoufmoghaddamChemistry Research Laboratory, Department of Chemistry, University of Oxford , Mansfield Road, Oxford OX1 3TA, United Kingdom.
Shabaz MohammedChemistry Research Laboratory, Department of Chemistry, University of Oxford , Mansfield Road, Oxford OX1 3TA, United Kingdom.ORCID 0000-0003-2640-9560
Timothy D W ClaridgeChemistry Research Laboratory, Department of Chemistry, University of Oxford , Mansfield Road, Oxford OX1 3TA, United Kingdom.ORCID 0000-0001-5583-6460
Andrew J BaldwinChemistry Research Laboratory, Department of Chemistry, University of Oxford , Mansfield Road, Oxford OX1 3TA, United Kingdom.
Benjamin G DavisChemistry Research Laboratory, Department of Chemistry, University of Oxford , Mansfield Road, Oxford OX1 3TA, United Kingdom.ORCID 0000-0002-5056-407X

Funding

Biotechnology and Biological Sciences Research Council BB/J014346/1British Heart FoundationCancer Research UK
6 · The paper itself

Abstract

Virus-like particles (VLPs) are stable protein cages derived from virus coats. They have been used extensively as biomolecular platforms, e.g., nanocarriers or vaccines, but a convenient in situ technique is lacking for tracking functional status. Here, we present a simple way to monitor disassembly of

Indexed as

Nuclear Magnetic Resonance, BiomolecularBacteriophage lambdaFluorineVaccines, Virus-Like ParticleViral ProteinsFluorineQ protein, Bacteriophage lambdaVaccines, Virus-Like ParticleViral Proteins

Identifiers

PMID28350443
PMCPMC5425944

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.