Evidence map›Paper›PMID 28350337›Full record

ArticleMolecules (Basel, Switzerland)2017

3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NFκB Signaling Pathways.

Wei Chao, Jeng-Shyan Deng, Pei-Ying Li, Yu-Chia Liang, Guan-Jhong Huang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 44 citations in OpenAlex.

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  12. Aqueous extracts ofOncology letters · 2021
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  13. Review
  14. Whole-genome sequence ofJournal of advanced research · 2020
    Article
  15. Article
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  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Wei ChaoSchool of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan. sebrina0427@hotmail.com.
Jeng-Shyan DengDepartment of Health and Nutrition Biotechnology, Asia University, Taichung 404, Taiwan. dengjs@asia.edu.tw.
Pei-Ying LiSchool of Pharmacy, College of Pharmacy, China Medical University, Taichung 404, Taiwan. chacolate042276@yahoo.com.tw.
Yu-Chia LiangSchool of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan. allen1987323@yahoo.com.tw.
Guan-Jhong HuangSchool of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan. gjhuang@mail.cmu.edu.tw.
China Medical University · TWAsia University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

3,4-Dihydroxybenzalactone (DBL) was isolated from

Indexed as

A549 CellsCarcinoma, Non-Small-Cell LungCell AdhesionCell MovementCell SurvivalDrug Screening Assays, AntitumorEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansLactonesLung NeoplasmsMAP Kinase Signaling SystemNeoplasm MetastasisNF-kappa BPhellinusPlant ExtractsLactonesNF-kappa BPhellinus linteus extractPlant ExtractsReactive Oxygen Speciescancer metastasisDBLEMTMMPsPhellinus linteusROS

Identifiers

PMID28350337
PMCPMC6154291
OpenAlexW2601209390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.