ReviewJournal of clinical medicine2017
Factor VII Deficiency: Clinical Phenotype, Genotype and Therapy.
Review in Journal of clinical medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Factor VII Padua: a systematic review of reported cases, diagnosis, clinical manifestations, and management strategies.Annals of hematology · 2026Pooled it
- Reproductive health and hemostatic issues in women and girls with congenital factor VII deficiency: A systematic review.Journal of thrombosis and haemostasis : JTH · 2022Pooled it
- Treatment of Deep Vein Thrombosis in Congenital Factor VII Deficiency: A Case Report and Literature Review.Clinical case reports · 2026Article
- Article
- Optimizing Surgical Approaches for Patients with Inherited Factor VII Deficiency.Thrombosis and haemostasis · 2026Article
- Perioperative Prophylaxis in Pediatric Factor VII Deficiency: Experience From Rabat Children's Hospital.Cureus · 2026Article
- Article
- Vitamin K-dependent and other rare coagulation factor deficiencies: a single-center experience.Italian journal of pediatrics · 2025Article
- Perioperative Challenges in a Patient With Moderate Congenital Factor VII Deficiency: A Case Report.Cureus · 2025Article
- Sustained high expression of human FVII following AAV8-mediated gene delivery in mice.Molecular therapy. Methods & clinical development · 2025Article
- Article
- Acute myeloid leukemia: A rare cause of acquired isolated factor VII deficiency.Leukemia research reports · 2025Article
- Bleeding Symptoms in Pediatric Patients with Congenital FVII Deficiency and Correlation to Thrombin Generation Assay Parameters: A Single-Center Retrospective Analysis.Life (Basel, Switzerland) · 2024Article
- Autoimmune Hepatitis Complicated by Undiagnosed Factor VII Deficiency: A Pitfall of Coagulopathy.Internal medicine (Tokyo, Japan) · 2024Article
- Rare inherited coagulation disorders: no longer orphan and neglected.Research and practice in thrombosis and haemostasis · 2024Review
- Factor VII Deficiency in an End-Stage Renal Disease Patient With Recurrent Thrombosis: A Case Report.Cureus · 2023Article
- Surgery in rare bleeding disorders: the prospective MARACHI study.Research and practice in thrombosis and haemostasis · 2023Article
- Acquired Isolated Factor VII Deficiency in Plasma Cell Dyscrasias: A Brief Presentation of Two Plasma-Cell-Leukemia-Related Cases and Review of Literature.Journal of clinical medicine · 2023Review
- Alert: Not All Acute Hepatitis with Raised INR is Acute Liver Failure!Indian journal of pediatrics · 2023Article
- Factor VII deficiency: a rare genetic bleeding disorder in a 7-year-old child: a case report.Journal of medical case reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Factor VII deficiency is the most common among rare inherited autosomal recessive bleeding disorders, and is a chameleon disease due to the lack of a direct correlation between plasma levels of coagulation Factor VII and bleeding manifestations. Clinical phenotypes range from asymptomatic condition-even in homozygous subjects-to severe life-threatening bleedings (central nervous system, gastrointestinal bleeding). Prediction of bleeding risk is thus based on multiple parameters that challenge disease management. Spontaneous or surgical bleedings require accurate treatment schedules, and patients at high risk of severe hemorrhages may need prophylaxis from childhood onwards. The aim of the current review is to depict an updated summary of clinical phenotype, laboratory diagnosis, and treatment of inherited Factor VII deficiency.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.