Trial reportFish physiology and biochemistry2017
Comparing the effects of different dietary organic acids on the growth, intestinal short-chain fatty acids, and liver histopathology of red hybrid tilapia (Oreochromis sp.) and potential use of these as preservatives.
Trial report in Fish physiology and biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 90 citations in OpenAlex.
- Endocrine-Nutritional Synergy Between Sex Inversion and Microencapsulated Bioactives Enhances Growth, Intestinal Development, and Oxidative Stability in Nile Tilapia Larvae.Journal of animal physiology and animal nutrition · 2026Article
- Countering the negative effects of dietary soybean (SB) meal in Nile tilapia with organic acid salts.Scientific reports · 2026Article
- Dietary organic acid blend modulates hemato-immunological parameters, digestive and reproductive performances in red tilapia (Oreochromis niloticus × O. mossambicus) broodstock.Fish physiology and biochemistry · 2025Article
- Dietary Hydrolyzed Yeast Improves Growth, Gut Health, and Selective Gene Expression of Nile Tilapia (Aquaculture nutrition · 2025Article
- Dietary Herbal Leaves Mixture Extract Enhances Growth, Antioxidant Status, and Resistance toAquaculture nutrition · 2025Article
- Evaluation of Gamma Aminobutyric Acid and Sodium Butyrate in Juvenile Red Seabream (Animals : an open access journal from MDPI · 2024Article
- DietaryAquaculture nutrition · 2024Article
- Eubiotic Effect of a Dietary Bio-AquaProbiotics and antimicrobial proteins · 2023Article
- Oleic acid as potential immunostimulant in metabolism pathways of hybrid grouper fingerlings (Epinephelus fuscoguttatus × Epinephelus lanceolatus) infected with Vibrio vulnificus.Scientific reports · 2023Article
- Effects of Dietary Lactic Acid Supplementation on the Activity of Digestive and Antioxidant Enzymes, Gene Expressions, and Bacterial Communities in the Intestine of Common Carp,Animals : an open access journal from MDPI · 2023Article
- Effects of sodium butyrate on growth performance, antioxidant status, inflammatory response and resistance to hypoxic stress in juvenile largemouth bass (Frontiers in immunology · 2023Article
- Comparison of Different Dietary Fatty Acids Supplement on the Immune Response of Hybrid Grouper (Biology · 2022Article
- Antibiotic accumulation, growth performance, intestinal diversification, and function of Nile tilapia (Oreochromis niloticus) feed by diets supplemented with different doses of sulfamethoxazole.Environmental science and pollution research international · 2021Article
- Effects of dietary sodium butyrate on growth, digestive enzymes, body composition and nutrient retention-related gene expression of juvenile yellow catfish (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2021Article
- Conserved anti-inflammatory effects and sensing of butyrate in zebrafish.Gut microbes · 2020Article
- Galactooligosaccharides and Resistant Starch Altered Microbiota and Short-Chain Fatty Acids in anFrontiers in microbiology · 2020Article
- Hepatic and gastroprotective activity of Serjania marginata leaf aqueous extract in Nile tilapia (Oreochromis niloticus).Fish physiology and biochemistry · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dietary organic acids are increasingly being investigated as a potential means of improving growth and nutrient utilization in aquatic animals. A 9-week study was performed to compare equal amounts (2%) of different organic acids (sodium butyrate, acetate, propionate, or formate) on the growth, muscle proximate composition, fatty acid composition, cholesterol and lipid peroxidation, differential cell counts, plasma biochemistry, intestinal short-chain fatty acid (SCFA) level, and liver histopathology to red hybrid tilapia (Oreochromis sp.) (initial mean weight of 2.87 g). A second experiment was performed to determine their effects on lipid peroxidation and trimethylamine (TMA) when added at 1% to tilapia meat and left out for 24 h. The results of the first experiment showed no treatment effect to growth, feeding efficiencies, or muscle fatty acid composition, but all dietary organic acids significantly decreased intestinal SCFA. Dietary butyrate and propionate significantly decreased muscle lipid peroxidation compared to the control group, but the dietary formate treatment had the lowest lipid peroxidation compared to all treatments. Muscle crude protein and lipid in tilapia fed the formate diet were significantly lower and higher, respectively, and showed evidence of stress based on the differential cell counts, significantly higher plasma glucose and liver glycogen, as well as inflammatory responses in the liver. Although a potential benefit of dietary organic acids was a reduction to lipid peroxidation, this could be accomplished post-harvest by direct additions to the meat. In addition, inclusions of butyrate and propionate to tilapia meat significantly decreased TMA, which might be a more cost-effective option to improve the shelf life of tilapia products.
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Registered trials
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