ArticleHead and neck pathology2017
Intraoral Salivary Duct Cyst: Clinical and Histopathologic Features of 177 Cases.
Article in Head and neck pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 49 citations in OpenAlex.
- Lacrimal gland duct obstruction and dacryops: Unravelling its pathogenesis with proteomics and cellular profiling.The ocular surface · 2026Article
- Concurrent occurrence of a salivary duct cyst and two mucoceles in the lower lip.Journal of dental sciences · 2025Article
- Salivary duct cyst of the upper lip.Journal of dental sciences · 2025Article
- Percutaneous injection of sclerosant agents as an effective treatment for cystic malformations of the head and neck.Oral and maxillofacial surgery · 2024Article
- Management of mucoid cysts of the oral cavity: Cases series and review.International journal of surgery case reports · 2024Article
- An Uncommon Salivary Gland Swelling- Parotid Duct Cyst and Its Management.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Duct ligation/de-ligation model: exploring mechanisms for salivary gland injury and regeneration.Frontiers in cell and developmental biology · 2024Review
- Top Ten Oncocytic Head and Neck Lesions to Contemplate.Head and neck pathology · 2023Review
- Myoepithelial Carcinoma Arising in a Salivary Duct Cyst of the Parotid Gland: Case Presentation.Medicina (Kaunas, Lithuania) · 2023Article
- Histomorphology and Immunohistochemistry of a Congenital Nephromegaly Demonstrate Concurrent Features of Heritable and Acquired Cystic Nephropathies in a Girgentana Goat (Case reports in veterinary medicine · 2021Article
- Case of a Large Oropharyngeal Cyst.Cureus · 2019Article
- Challenges in Minor Salivary Gland Biopsies: A Practical Approach to Problematic Histologic Patterns.Head and neck pathology · 2019Review
- Diagnostic Approach to Fine Needle Aspirations of Cystic Lesions of the Salivary Gland.Head and neck pathology · 2018Review
- Clinical characteristics, demographic trends, and management outcomes of oral mucoceles: A 10-year retrospective study.Journal of oral and maxillofacial pathology : JOMFPArticle
- Oral mucoceles: A Brazillian Multicenter Study of 1,901 Cases.Brazilian dental journalArticle
- Intraoral salivary duct cyst: Report of rare entity.Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The salivary duct cyst (SDC) is a reactive ductal ectasia most frequently seen in major salivary glands, and likely caused by obstruction. The aim of this study is to define the clinical and histopathologic spectrum of intraoral SDCs. Cases were retrieved from the archives of Harvard School of Dental Medicine/StrataDx, Inc. from January 2012 to August 2014. There were 177 cases of which 103 (58.2%) occurred in females, with a median age of 56 (range 2-95). Approximately half of cases (45.8%) presented in the area of the buccal mucosa, lower lip mucosa, or mandibular vestibule, and 23.2% presented in the floor of mouth. SDCs were lined at least focally by 1-2 layers of cuboidal/columnar epithelium in 85.3% of cases and showed varying degrees of metaplasia (oncocytic, mucous cell, squamous, ciliated, apocrine-like) in 68.4% of cases. Intraluminal mucous stasis was present in 41.8% of SDCs, incipient calcification was present within 4.5% of SDCs, and chronic obstructive sialadenitis was seen in 90.2% of cases. No cysts showed adenomatous ductal proliferations or true papillary structures with fibrovascular cores, although 41.2% exhibited reactive undulation of cyst lining. Thirty-nine 'papillary oncocytic cystadenoma-like' SDCs (22.0%) demonstrated complete oncocytic metaplasia and marked undulation. An additional seven such cysts (4.0%) had a 'Warthin tumor-like' lymphoplasmacytic infiltrate. Intraoral SDCs occur most commonly in the sixth decade of life in locations distinct from extravasation mucoceles, likely secondary to intraluminal obstruction. SDCs show diverse histopathology and certain phenotypic variants may be mistaken for papillary oncocytic cystadenoma or Warthin tumor.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.