Evidence map›Paper›PMID 28349316›Full record

ReviewCurrent psychiatry reports2017

Cannabis, Cannabinoids, and Sleep: a Review of the Literature.

Kimberly A Babson, James Sottile, Danielle Morabito

3 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Current psychiatry reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 206 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
206citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03210766 completednot on this map

Nabilone and THC/CBD for the Treatment of FBSS Refractory Pain

TypeobservationalSponsorAzienda Ospedaliera Universitaria Policlinico "G. Martino"Ran2014 to 2016Enrolled20ConditionsFBSSArmsNabilone, THC/CBD
NCT05041647 phase2completednot on this mapstarted 2023, after this paper: background citation

A Pilot, Double-Blind, Randomized, Placebo-Controlled Trial Evaluating the Efficacy and Safety of a Cannabis-Infused Oil For Treatment of Insomnia in Major Depression

TypeinterventionalSponsorSt. Joseph's Healthcare HamiltonRan2023 to 2025Enrolled14ConditionsInsomnia, Depressive Disorder, Major, Sleep Disorder, DepressionArms25:1 CBD/THC, 5:1 CBD/THC, Placebo
NCT05269459 phase2recruitingnot on this mapstarted 2022, after this paper: background citation

Safety and Efficacy of Cannabidiol (CBD) for Symptoms of Post-Traumatic Stress Disorder (PTSD) in Adults Using Liquid StructureTM Formulation (NantheiaTM ATL5).

TypeinterventionalSponsorUniversity of NebraskaRan2022 to 2029Enrolled180ConditionsPTSDArmsCannabidiol Administered as Nantheia ATL5, Placebo
3 · Its place in the literature

Who cites it

206 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Systematic review of drugs that modify the circadian system's phase-shifting responses to light exposure.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Daily-level associations between sleep hygiene, cannabis use, and sleep health outcomes.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. The effects of tetrahydrocannabinol and cannabidiol on sleep in cancer patients.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  16. Review
  17. Article
  18. Interactions between cannabis use and chronic pain on sleep architecture: Findings from in-home EEG recordings.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Article
  19. Article
  20. Article

146 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kimberly A BabsonNational Center for PTSD-Dissemination & Training Division, VA Palo Alto Health Care System, 795 Willow Road, Menlo Park, CA, 94025, USA. Kimberly.Babson@va.gov.
James SottilePalo Alto University, Palo Alto, CA, USA.
Danielle MorabitoNational Center for PTSD-Dissemination & Training Division, VA Palo Alto Health Care System, 795 Willow Road, Menlo Park, CA, 94025, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe current review aims to summarize the state of research on cannabis and sleep up to 2014 and to review in detail the literature on cannabis and specific sleep disorders from 2014 to the time of publication. RECENT

findingsPreliminary research into cannabis and insomnia suggests that cannabidiol (CBD) may have therapeutic potential for the treatment of insomnia. Delta-9 tetrahydrocannabinol (THC) may decrease sleep latency but could impair sleep quality long-term. Novel studies investigating cannabinoids and obstructive sleep apnea suggest that synthetic cannabinoids such as nabilone and dronabinol may have short-term benefit for sleep apnea due to their modulatory effects on serotonin-mediated apneas. CBD may hold promise for REM sleep behavior disorder and excessive daytime sleepiness, while nabilone may reduce nightmares associated with PTSD and may improve sleep among patients with chronic pain. Research on cannabis and sleep is in its infancy and has yielded mixed results. Additional controlled and longitudinal research is critical to advance our understanding of research and clinical implications.

Indexed as

CannabisLong Term Adverse EffectsSleep Initiation and Maintenance DisordersCannabinoidsDreamsHumansSleepCannabinoidsCannabinoidsCannabisInsomniaSleepSleep apnea

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.