Evidence map›Paper›PMID 28349300›Full record

ReviewFrontiers of medicine2017

Behavioral methods for the functional assessment of hair cells in zebrafish.

Qin Yang, Peng Sun, Shi Chen, Hongzhe Li, Fangyi Chen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Frontiers of medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. TheInternational journal of molecular sciences · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Frontiers in cell and developmental biology · 2021
    Article
  10. Use of Zebrafish in Drug Discovery Toxicology.Chemical research in toxicology · 2020
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Qin YangDepartment of Biology, South University of Science and Technology of China, Shenzhen, 518000, China.
Peng SunState Key Laboratory of Analog and Mixed-Signal VLSI, University of Macau, Macau, China.
Shi ChenKey Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, and Medical Research Institute, Wuhan University, Wuhan, 430072, China.
Hongzhe LiResearch Service, VA Loma Linda Healthcare System, Loma Linda, CA, 92357, USA. hongzhe@gmail.com.
Fangyi ChenDepartment of Biology, South University of Science and Technology of China, Shenzhen, 518000, China. chenfy@sustc.edu.cn.
Wuhan University · CNSouthern University of Science and Technology · CNUniversity of Macau · MOVA Loma Linda Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zebrafish is an emerging animal model for studies on auditory system. This model presents high comparability with humans, good accessibility to the hearing organ, and high throughput capacity. To better utilize this animal model, methodologies need to be used to quantify the hearing function of the zebrafish. Zebrafish displays a series of innate and robust behavior related to its auditory function. Here, we reviewed the advantage of using zebrafish in auditory research and then introduced three behavioral tests, as follows: the startle response, the vestibular-ocular reflex, and rheotaxis. These tests are discussed in terms of their physiological characteristics, up-to-date technical development, and apparatus description. Test limitation and areas to improve are also introduced. Finally, we revealed the feasibility of these applications in zebrafish behavioral assessment and their potential in the high-throughput screening on hearing-related genes and drugs.

Indexed as

Behavior, AnimalAnimalsBehavior Rating ScaleHair Cells, AuditoryHigh-Throughput Screening AssaysHumansModels, AnimalReflex, StartleZebrafishauditorybehaviorrheotaxisstartle responsevestibular-ocular reflexzebrafish (Danio rerio)

Identifiers

PMID28349300
OpenAlexW2601419836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.