ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2017
Variability in medication taking is associated with cognitive performance in nondemented older adults.
Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02566239 (Ambient Independence Measures for Guiding Care Transitions), which is not on this map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ambient Independence Measures for Guiding Care Transitions
Who cites it
30 citing papers in PubMed.
- Older adults' views of passive smartphone monitoring for dementia risk: a multi-method analysis.Innovation in aging · 2026Article
- Difficulty with taking medications and the future risk of Alzheimer's disease and related dementias: Health and Retirement Study of Americans.American journal of neurodegenerative disease · 2026Article
- Smart home Internet of Things-based behavioural analysis for early detection of cognitive decline: toward Saudi future vision.mHealth · 2026Article
- Exploring Factors Affecting Verbal Fluency in Healthy Aging.Annals of the New York Academy of Sciences · 2025Article
- Medication Management Difficulty, Medication Nonadherence, and Risk of Hospitalization Among Cognitively Impaired Older Americans: A Nationally Representative Study.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025Article
- Factors associated with cognitive flexibility in people with opioid-use disorder: a pilot study.Frontiers in psychiatry · 2024Article
- Using Continuous Passive Assessment Technology to Describe Health and Behavior Patterns Preceding and Following a Cancer Diagnosis in Older Adults: Proof-of-Concept Case Series Study.JMIR formative research · 2023Article
- Article
- Unobtrusive Sensing Technology Detects Ecologically Valid Spatiotemporal Patterns of Daily Routines Distinctive to Persons With Mild Cognitive Impairment.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Capturing Cognitive Aging in Vivo: Application of a Neuropsychological Framework for Emerging Digital Tools.JMIR aging · 2022Article
- Unobtrusive, in-home assessment of older adults' everyday activities and health events: associations with cognitive performance over a brief observation period.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2022Article
- Online monitoring of financial capacity in older adults: Feasibility and initial findings.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- Application of In-Home Monitoring Data to Transition Decisions in Continuing Care Retirement Communities: Usability Study.Journal of medical Internet research · 2021Article
- Reproducibility and replicability of high-frequency, in-home digital biomarkers in reducing sample sizes for clinical trials.Alzheimer's & dementia (New York, N. Y.) · 2021Article
- Passively-Measured Routine Home Computer Activity and Application Use Can Detect Mild Cognitive Impairment and Correlate with Important Cognitive Functions in Older Adulthood.Journal of Alzheimer's disease : JAD · 2021Article
- Analyzing Sensor-Based Individual and Population Behavior Patterns via Inverse Reinforcement Learning.Sensors (Basel, Switzerland) · 2020Article
- Feasibility of In-Home Sensor Monitoring to Detect Mild Cognitive Impairment in Aging Military Veterans: Prospective Observational Study.JMIR formative research · 2020Article
- Smart Environments and Social Robots for Age-Friendly Integrated Care Services.International journal of environmental research and public health · 2020Article
- An Ecologically Valid, Longitudinal, and Unbiased Assessment of Treatment Efficacy in Alzheimer Disease (the EVALUATE-AD Trial): Proof-of-Concept Study.JMIR research protocols · 2020Article
- The relationships between cognitive function, literacy and HIV status knowledge among older adults in rural South Africa.Journal of the International AIDS Society · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Interventions to slow cognitive decline typically can do little to reverse decline. Thus, early detection methods are critical. However, tools like cognitive testing are time consuming and require costly expertise. Changes in activities of daily living such as medication adherence may herald the onset of cognitive decline before clinical standards. Here, we determine the relationship between medication adherence and cognitive function in preclinical older adults. We objectively assessed medication adherence in 38 older adults (mean age 86.7 ± 6.9 years). Our results demonstrate that individuals with lower cognitive function have more spread in the timing of taking their medications (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.