Dataset of the human homologues and orthologues of lipid-metabolic genes identified as DAF-16 targets their roles in lipid and energy metabolism.

Lavender Yuen-Nam Fan, Paula Saavedra-García, Eric Wing-Fai Lam

Open access · goldAbstract read

In one paragraph

Article in Data in brief, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.2field-weighted citation impact, top 45% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

FOXM1 maintains fatty acid homoeostasis through the SET7-H3K4me1-FASN axis.Cell death discovery · 2023
Article
Close association between abnormal expressed enzymes of energy metabolism and diarrhea-predominant irritable bowel syndrome.Chinese medical journal · 2019
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lavender Yuen-Nam FanDepartment of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London W12 0NN, UK.

Paula Saavedra-GarcíaDepartment of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London W12 0NN, UK.

Eric Wing-Fai LamDepartment of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London W12 0NN, UK.

Imperial College London · GBHammersmith Hospital · GB

Funding

Breast Cancer Now 2012MAYPR070Breast Cancer Now 2012NOVPHD016

6 · The paper itself

Abstract

The data presented in this article are related to the review article entitled 'Unravelling the role of fatty acid metabolism in cancer through the FOXO3-FOXM1 axis' (Saavedra-Garcia et al., 2017) [24]. Here, we have matched the DAF-16/FOXO3 downstream genes with their respective human orthologues and reviewed the roles of these targeted genes in FA metabolism. The list of genes listed in this article are precisely selected from literature reviews based on their functions in mammalian FA metabolism. The nematode

Indexed as

ACAA2, Acetyl-CoA acetyltransferase 2ACACA, Acetyl-CoA carboxylaseACAD8, Acyl-CoA dehydrogenase family member 8ACADM, Acyl-CoA dehydrogenase C4 to C12 straight chainACOX, Acyl-CoA oxidaseACSL3/4, Acyl-CoA synthetase long-chain family member 3/4ACSS, Acyl-CoA synthetase short-chain family memberCaenorhabditis elegansCPT2, Carnitine palmitoyltransferase IIDAF-16DAG, DiacylglycerolDGAT, Diacylglycerol O-acyltransferaseECHS1, Short-chain enoyl-CoA hydratase 1ELOVL1, Elongation of very long chain fatty acids protein 1FADS2, Fatty acid desaturase 2FA, fatty acidFASN, Fatty acid synthaseFATP4, Fatty acid transport protein 4FOX, Forkhead boxFOXM1FOXO3HADHA, Hydroxyacyl-CoA dehydrogenase/3-Ketoacyl-CoA thiolase/Enoyl-CoA hydratase, alpha subunitHADH, Hydroxyacyl-coenzyme A dehydrogenaseLCFA, Long chain fatty acidLipid metabolismMLYCD, Malonyl-CoA decarboxylaseMOGAT1/2, Monoacylglycerol O-acyltransferase 1/2PNPLA, patatin like phospholipase domain containingPUFA, polyunsaturated fatty acidSCD1/5, Stearoyl-CoA desaturase 1/5TAG, triacylglycerolTCA, Tricarboxylic acidVLCFA, Very long chain fatty acid.

Identifiers

PMID28349111

DOI10.1016/j.dib.2017.02.055

PMCPMC5358523

OpenAlexW2594003742

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.