Evidence map›Paper›PMID 28349094›Full record

ReviewTemperature (Austin, Tex.)2017

Current concepts of active vasodilation in human skin.

Brett J Wong, Casey G Hollowed

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Temperature (Austin, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03618524 (Effect of Local Heat Stress Via Leg Bath on Artery Function), which is not on this map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03618524 nacompletednot on this mapstarted 2019, after this paper: background citation

Effect of Local Heat Stress Via Leg Bath on Artery Function

TypeinterventionalSponsorMcMaster UniversityRan2019 to 2019Enrolled16ConditionsEndothelial DysfunctionArmsLower limb hot water immersion
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 78 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Narrative Review on Infants' Thermoregulatory Response to Heat.International journal of environmental research and public health · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Effects of menopause on temperature regulation.Temperature (Austin, Tex.) · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Brett J WongDepartment of Kinesiology & Health, Georgia State University, Atlanta, GA, USA.
Casey G HollowedDepartment of Kinesiology & Health, Georgia State University, Atlanta, GA, USA.
Georgia State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In humans, an increase in internal core temperature elicits large increases in skin blood flow and sweating. The increase in skin blood flow serves to transfer heat via convection from the body core to the skin surface while sweating results in evaporative cooling of the skin. Cutaneous vasodilation and sudomotor activity are controlled by a sympathetic cholinergic active vasodilator system that is hypothesized to operate through a co-transmission mechanism. To date, mechanisms of cutaneous active vasodilation remain equivocal despite many years of research by several productive laboratory groups. The purpose of this review is to highlight recent advancements in the field of cutaneous active vasodilation framed in the context of some of the historical findings that laid the groundwork for our current understanding of cutaneous active vasodilation.

Indexed as

hyperthermiamicrodialysisneurokinin-1 receptorsneuropeptides EDHFnitric oxidesympathetic nervous systemthermoregulationvasoactive intestinal polypeptide

Identifiers

PMID28349094
PMCPMC5356216
OpenAlexW2469780980

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.