Evidence map›Paper›PMID 28349020›Full record

ArticleAdvanced biomedical research2017

Treatment Outcome of the Drug-resistant Zoonotic Cutaneous Leishmaniasis by Glucantime.

Simindokht Soleimanifard, Reza Arjmand, Sedighe Saberi, Mansoor Salehi, Seyed Hossain Hejazi

Abstract read
In one paragraph

Article in Advanced biomedical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Simindokht SoleimanifardDepartment of Parasitology, School of Medicine, Isfahan University of Medical Sciences and Health Services, Isfahan, Iran.
Reza ArjmandDepartment of Parasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Sedighe SaberiDepartment of Parasitology, School of Medicine, Isfahan University of Medical Sciences and Health Services, Isfahan, Iran.
Mansoor SalehiDepartment of Anatomical Sciences and Molecular Biology, Medical School, Isfahan University of Medical Sciences and Health Services, Isfahan, Iran.
Seyed Hossain HejaziDepartment of Parasitology, School of Medicine, Isfahan University of Medical Sciences and Health Services, Isfahan, Iran; Department of Parasitology, Skin Disease and Leishmaniasis Research Center, School of Medicine, Isfahan University of Medical Sciences and Health Services, Isfahan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResistance of MATERIALS AND

methodsSamples were taken from 10 cutaneous leishmaniasis (CL) patients who had not responded to chemotherapy with Glucantime. Nested polymerase chain reaction (PCR) was performed to identify the isolated species. Stationary phase promastigotes were added to the grown, adhesive J774 macrophages. Values obtained from standard strain were compared with the test cultures after exposure to the medicine.

resultsThe results of amplified band on agarose gel demonstrated all samples were

conclusionPentavalent antimonial (SbV) salts are the main component of chemotherapy against leishmaniasis. However, the medicine has been found ineffective. In the present study, isolates from patients with no response to treatment had no significant difference from the standard

Indexed as

GlucantimeLeishmaniaLeishmania majorresistancetreatment

Identifiers

PMID28349020
PMCPMC5353763

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.