Evidence map›Paper›PMID 28348980›Full record

ArticleFrontiers in cellular and infection microbiology2017

Overexpression of the Endosomal Anion/Proton Exchanger ClC-5 Increases Cell Susceptibility toward

Frederike Ruhe, Alexandra Olling, Rasmus Abromeit, Dennis Rataj, Matthias Grieschat, Andre Zeug, Ralf Gerhard, Alexi Alekov

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Frederike RuheInstitute for Neurophysiology, Hannover Medical School Hannover, Germany.
Alexandra OllingInstitute for Toxicology, Hannover Medical School Hannover, Germany.
Rasmus AbromeitInstitute for Neurophysiology, Hannover Medical School Hannover, Germany.
Dennis RatajInstitute for Toxicology, Hannover Medical School Hannover, Germany.
Matthias GrieschatInstitute for Neurophysiology, Hannover Medical School Hannover, Germany.
Andre ZeugInstitute for Neurophysiology, Hannover Medical School Hannover, Germany.
Ralf GerhardInstitute for Toxicology, Hannover Medical School Hannover, Germany.
Alexi AlekovInstitute for Neurophysiology, Hannover Medical School Hannover, Germany.
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virulent

Indexed as

Bacterial ProteinsBacterial ToxinsBoron CompoundsCell LineCell SurvivalChloride ChannelsClostridioides difficileEnterotoxinsHumansHydrogen-Ion ConcentrationBacterial ProteinsBacterial ToxinsBoron CompoundsChloride ChannelsCLC-5 chloride channelEnterotoxinstcdA protein, Clostridium difficiletoxB protein, Clostridium difficiletrimethylaminocarboxyldihydroboranC. difficileClC-5CLC proteinsCLC transportendocytosisendosomal acidificationTcdATcdB

Identifiers

PMID28348980
PMCPMC5346576
OpenAlexW2592482242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.