Evidence map›Paper›PMID 28348972›Full record

ArticleAvicenna journal of phytomedicine

Antidiabetic, hypolipidemic and hepatoprotective effects of

Akram Ahangarpour, Hamid Heidari, Ali Akbar Oroojan, Farhang Mirzavandi, Khalil Nasr Esfehani, Zeinab Dehghan Mohammadi

Open access · greenAbstract read
In one paragraph

Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 63 citations in OpenAlex.

  1. Unveiling the Antihyperglycemic Potential ofFoods (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Review
  4. Fluorinated indeno-quinoxaline bearing thiazole moieties as hypoglycaemic agents targetingJournal of enzyme inhibition and medicinal chemistry · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Mechanistic insights on burdock (Food science and biotechnology · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. The effect of hydroalcoholic extract ofInternational journal of reproductive biomedicine · 2021
    Article
  13. Review
  14. Review
  15. In vitro evaluation of commercial foam Belcils® on Acanthamoeba spp.International journal for parasitology. Drugs and drug resistance · 2020
    Article
  16. Review
  17. Review
  18. 3'-Molecules (Basel, Switzerland) · 2019
    Article
  19. Frontiers in plant science · 2019
    Review
  20. Wound Healing and the Use of Medicinal Plants.Evidence-based complementary and alternative medicine : eCAM · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Akram AhangarpourHealth Research Institute, Diabetes Research Center, Department of Physiology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Hamid HeidariDepartment of Physiology, Health Research Institute, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Department of Physiology, School of Medicine, Qom University of Medical Sciences, Qom, Iran.
Ali Akbar OroojanDepartment of Physiology, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Farhang MirzavandiDepartment of Nutrition, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Khalil Nasr EsfehaniDepartment of Nutrition, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Zeinab Dehghan MohammadiHealth Research Institute, Diabetes Research Center, Department of Physiology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Ahvaz Jundishapur University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMATERIALS AND

methodsIn this investigation, 70 adult male NMRI mice (30-35g) randomly divided into 7 groups (n=10) as follow: 1-control, 2-type 2 diabetic mice, 3-diabetic mice that received glibenclamide (0.25 mg/kg) as an anti-diabetic drug, 4, 5, 6 and 7- diabetic and normal animals that were pre-treated with 200 and 300 mg/kg

resultsInduction of diabetes decreased the level of insulin, leptin and high density lipoprotein (HDL) and increased the level of other lipids, glucose, and hepatic enzymes significantly (p<0.05). Administration of both doses of the extract significantly decreased the level of triglyceride, very low density lipoprotein, glucose and alkaline phosphatase in diabetic mice (p<0.05). Insulin levels increased in animals treated with 200 mg/kg (p<0.05) and HDL and leptin levels increased in animals treated with 300 mg/kg of the extract (p<0.01).

conclusionThe results showed that

Indexed as

Arctium LappaHepatic enzymeInsulinLipid profileType 2 diabetes

Identifiers

PMID28348972
PMCPMC5355822
OpenAlexW2582168232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.