Evidence map›Paper›PMID 28348967›Full record

ArticleAvicenna journal of phytomedicine

Preventive effect of

Mojtaba Pourzaki, Mansour Homayoun, Saeed Sadeghi, Masoumeh Seghatoleslam, Mahmoud Hosseini, Alireza Ebrahimzadeh Bideskan

Abstract read
In one paragraph

Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Direct Evidence for UsingAntioxidants (Basel, Switzerland) · 2023
    Article
  3. Molecules (Basel, Switzerland) · 2023
    Review
  4. KCNQ Potassium Channels as Targets of Botanical Folk Medicines.Annual review of pharmacology and toxicology · 2022
    Review
  5. Review
  6. EXCLI journal · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Neuroprotective effects ofAvicenna journal of phytomedicine
    Article
  12. Morphohistometric analysis of the effects ofAvicenna journal of phytomedicine
    Article
  13. Neuroprotective effects ofAvicenna journal of phytomedicine
    Review
  14. Article
  15. Protective impact ofAvicenna journal of phytomedicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mojtaba PourzakiDepartment of Anatomy and Cell Biology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mansour HomayounPharmacological Research Center of Medicinal Plants , School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Saeed SadeghiDepartment of Anatomy and Cell Biology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Masoumeh SeghatoleslamDepartment of Anatomy and Cell Biology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran ; Microanatomy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahmoud HosseiniNeurocognitive Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Alireza Ebrahimzadeh BideskanDepartment of Anatomy and Cell Biology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran ; Microanatomy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMATERIALS AND

methodsForty male rats were divided into five main groups and treated by (1) saline, (2) PTZ: 100 mg/kg PTZ (i.p) and (3-5) 50, 100 and 200 mg/kg of hydro-alcoholic extract of

resultsAll doses of the extract reduced duration, frequency and amplitude of the burst discharges while prolonged the latency of the seizure attacks (p<0.05, p<0.01, and p<0.001). Administration of all 3 doses of the extract significantly prevented from production of dark neurons (p<0.01, and p<0.001) and apoptotic cells (p<0.05, p<0.01, and p<0.001) in different areas of the hippocampus compared to PTZ group.

conclusionThe results of this study allow us to conclude that

Indexed as

ApoptosisCoriandrum sativumDamageHippocampusNeuronalSeizure

Identifiers

PMID28348967
PMCPMC5355817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.