Evidence map›Paper›PMID 28348833›Full record

ArticleMicrobial genomics2016

Microreact: visualizing and sharing data for genomic epidemiology and phylogeography.

Silvia Argimón, Khalil Abudahab, Richard J E Goater, Artemij Fedosejev, Jyothish Bhai, Corinna Glasner, Edward J Feil, Matthew T G Holden, Corin A Yeats, Hajo Grundmann and 2 more

Abstract read
In one paragraph

Article in Microbial genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 541 papers.

0numbers the graph read from it
0cells of the map it votes in
541citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

541 citing papers in PubMed.

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  11. Phenotypic and genotypic characterization ofJAC-antimicrobial resistance · 2026
    Article
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481 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Silvia Argimón1​The Centre for Genomic Pathogen Surveillance, Wellcome Genome Campus, Hinxton CB10 1SA, UK.
Khalil Abudahab1​The Centre for Genomic Pathogen Surveillance, Wellcome Genome Campus, Hinxton CB10 1SA, UK.
Richard J E Goater1​The Centre for Genomic Pathogen Surveillance, Wellcome Genome Campus, Hinxton CB10 1SA, UK.
Artemij Fedosejev2​Department of Infectious Disease Epidemiology, Imperial College London, London W2 1PG, UK.
Jyothish Bhai1​The Centre for Genomic Pathogen Surveillance, Wellcome Genome Campus, Hinxton CB10 1SA, UK.
Corinna Glasner1​The Centre for Genomic Pathogen Surveillance, Wellcome Genome Campus, Hinxton CB10 1SA, UK.
Edward J Feil3​The Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath, Bath, UK.
Matthew T G Holden4​School of Medicine, University of St. Andrews, St. Andrew, UK.
Corin A Yeats1​The Centre for Genomic Pathogen Surveillance, Wellcome Genome Campus, Hinxton CB10 1SA, UK.
Hajo Grundmann5​Department of Infection Prevention and Hospital Hygiene, University Medical Centre Freiburg, Freiburg, Germany.
Brian G Spratt2​Department of Infectious Disease Epidemiology, Imperial College London, London W2 1PG, UK.
David M Aanensen1​The Centre for Genomic Pathogen Surveillance, Wellcome Genome Campus, Hinxton CB10 1SA, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Visualization is frequently used to aid our interpretation of complex datasets. Within microbial genomics, visualizing the relationships between multiple genomes as a tree provides a framework onto which associated data (geographical, temporal, phenotypic and epidemiological) are added to generate hypotheses and to explore the dynamics of the system under investigation. Selected static images are then used within publications to highlight the key findings to a wider audience. However, these images are a very inadequate way of exploring and interpreting the richness of the data. There is, therefore, a need for flexible, interactive software that presents the population genomic outputs and associated data in a user-friendly manner for a wide range of end users, from trained bioinformaticians to front-line epidemiologists and health workers. Here, we present Microreact, a web application for the easy visualization of datasets consisting of any combination of trees, geographical, temporal and associated metadata. Data files can be uploaded to Microreact directly via the web browser or by linking to their location (e.g. from Google Drive/Dropbox or via API), and an integrated visualization via trees, maps, timelines and tables provides interactive querying of the data. The visualization can be shared as a permanent web link among collaborators, or embedded within publications to enable readers to explore and download the data. Microreact can act as an end point for any tool or bioinformatic pipeline that ultimately generates a tree, and provides a simple, yet powerful, visualization method that will aid research and discovery and the open sharing of datasets.

Indexed as

SoftwareGenomicsInformation DisseminationInternetMicrobiological TechniquesMolecular EpidemiologyPhylogeographyOpen dataphylogenomicsphylogeographypopulation genomicstrees

Identifiers

PMID28348833
PMCPMC5320705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.