Evidence map›Paper›PMID 28348811›Full record

ArticleMicrobial genomics2015

Large tandem chromosome expansions facilitate niche adaptation during persistent infection with drug-resistant

Wei Gao, Ian R Monk, Nicholas J Tobias, Simon L Gladman, Torsten Seemann, Timothy P Stinear, Benjamin P Howden

Open access · hybridAbstract read
In one paragraph

Article in Microbial genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Insights into antibiotic resistance promoted by quinolone exposure.Antimicrobial agents and chemotherapy · 2025
    Article
  4. Antibiotic resistance mediated by gene amplifications.npj antimicrobials and resistance · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Frontiers in cellular and infection microbiology · 2022
    Review
  10. Article
  11. Article
  12. Persistence ofFrontiers in microbiology · 2020
    Review
  13. Unstable chromosome rearrangements inProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  14. Article
  15. Tandem Amplification of the Staphylococcal Cassette ChromosomeAntimicrobial agents and chemotherapy · 2017
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Wei GaoMicrobiological Diagnostic Unit Public Health Laboratory, University of Melbourne, Doherty Institute for Infection and Immunity, Parkville, Victoria 3010, Australia.
Ian R MonkDepartment of Microbiology and Immunology, University of Melbourne, Doherty Institute for Infection and Immunity, Parkville, Victoria 3010, Australia.
Nicholas J TobiasDepartment of Microbiology and Immunology, University of Melbourne, Doherty Institute for Infection and Immunity, Parkville, Victoria 3010, Australia.
Simon L GladmanVictorian Life Sciences Computation Initiative, University of Melbourne, Parkville, Victoria 3010, Australia.
Torsten SeemannVictorian Life Sciences Computation Initiative, University of Melbourne, Parkville, Victoria 3010, Australia.
Timothy P StinearDepartment of Microbiology and Immunology, University of Melbourne, Doherty Institute for Infection and Immunity, Parkville, Victoria 3010, Australia.
Benjamin P HowdenMicrobiological Diagnostic Unit Public Health Laboratory, University of Melbourne, Doherty Institute for Infection and Immunity, Parkville, Victoria 3010, Australia.
University of Melbourne · AUAustin Hospital · AUMelbourne Bioinformatics · AUPeter Doherty Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We used genomics to study the evolution of meticillin-resistant

Indexed as

antibiotic resistancechromosome duplicationevolutiongenomicsmutationStaphylococcus aureus

Identifiers

PMID28348811
PMCPMC5320569
OpenAlexW2212104386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.