Evidence map›Paper›PMID 28348750›Full record

ArticleJMM case reports2016

Comprehensive pathogen detection associated with four recurrent episodes of Kawasaki disease in a patient during a single year using next-generation sequencing.

Hiromichi Hamada, Tsuyoshi Sekizuka, Kunihiro Oba, Harutaka Katano, Akiko Kinumaki, Masaru Terai, Tetsuya Mizutani, Makoto Kuroda

Open access · hybridAbstract readCase Reports
In one paragraph

Article in JMM case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Diagnosis of Kawasaki disease.International journal of rheumatic diseases · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Hiromichi HamadaDepartment of Pediatrics, Tokyo Women's Medical University Yachiyo Medical Center , 477-96 Owada-Shinden, Yachiyo, Chiba 2768524 , Japan.
Tsuyoshi SekizukaLaboratory of Bacterial Genomics, Pathogen Genomics Center, National Institute of Infectious Diseases , 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640 , Japan.
Kunihiro ObaDepartment of Pediatrics, Showa General Hospital , 2-450 Tenjin, Kodaira, Tokyo 187-8510 , Japan.
Harutaka KatanoDepartment of Pathology, National Institute of Infectious Diseases , 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640 , Japan.
Akiko KinumakiLaboratory of Bacterial Genomics, Pathogen Genomics Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan; Department of Pediatrics, Graduate School of Medicine, University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Masaru TeraiDepartment of Pediatrics, Tokyo Women's Medical University Yachiyo Medical Center , 477-96 Owada-Shinden, Yachiyo, Chiba 2768524 , Japan.
Tetsuya MizutaniDepartment of Virology 1, National Institute of Infectious Diseases, 4-7-1 Gakuen Musashimurayama, Tokyo 208-0011, Japan; Faculty of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwaicho, Fuchu City, Tokyo 183-8509, Japan.
Makoto KurodaLaboratory of Bacterial Genomics, Pathogen Genomics Center, National Institute of Infectious Diseases , 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640 , Japan.
National Institute of Infectious Diseases · JPShowa General Hospital · JPTokyo University of Agriculture and Technology · JPTokyo Women's Medical University · JPTokyo Women's Medical University Yachiyo Medical Center

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionKawasaki disease (KD) is the most common multisystem vasculitis in childhood. Pathogens can be associated with the onset of KD. However, a lack of consistency prevails among reports about this disease. CASE PRESENTATION: For this case of a 1-year-old boy with four recurrent episodes of KD within a year, we analysed profiles of pathogen reads in his serum and pharynx specimens using next-generation sequencing. Comparative analysis of the identified bacterial reads from serum samples found significant correlation of bacteria such as

conclusionIn this case,

Indexed as

cervical lymphadenopathyconjunctival injection, injected lips/pharynx, IVIG+antibiotic treatment, Kawasaki diseaseoedema/erythema of extremities, rash, vasculitis/fever

Identifiers

PMID28348750
PMCPMC5343132
OpenAlexW2329171825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.