Evidence map›Paper›PMID 28348596›Full record

ArticleInternational journal of dentistry2017

Genetic Association of

D D Lewis, J R Shaffer, E Feingold, M Cooper, M M Vanyukov, B S Maher, R L Slayton, M C Willing, S E Reis, D W McNeil and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of dentistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Allelic and Genotypic Distribution ofClinics and practice · 2025
    Article
  3. Review
  4. Article
  5. The association betweenHealth science reports · 2023
    Article
  6. Review
  7. Article
  8. Genetic Aspects of Dental Erosive Wear and Dental Caries.International journal of dentistry · 2021
    Review
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

D D LewisDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0003-0824-0773
J R ShafferDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0003-1897-1131
E FeingoldDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA; Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
M CooperCenter for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
M M VanyukovDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
B S MaherDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
R L SlaytonDepartment of Pediatric Dentistry, School of Dentistry, University of Washington, Seattle, WA, USA.
M C WillingDivision of Genetics and Genomic Medicine, Department of Pediatrics, School of Medicine, Washington University at St. Louis, St. Louis, MO, USA.
S E ReisDepartment of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Clinical and Translational Science Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
D W McNeilPsychology, Dental Practice and Rural Health, West Virginia University, Morgantown, WV, USA.ORCID 0000-0002-0766-8455
R J CroutDepartment of Periodontics, School of Dentistry, West Virginia University, Morgantown, WV, USA.
R J WeyantDepartment of Dental Public Health and Information Management, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
S M LevyDepartment of Preventive and Community Dentistry, University of Iowa College of Dentistry, Iowa City, IA, USA; Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA, USA.
A R VieiraCenter for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0003-3392-6881
M L MarazitaDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA; Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Clinical and Translational Science Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · USWest Virginia University · USJohns Hopkins University · USUniversity of Iowa · USUniversity of Washington · USWashington University in St. Louis · US

Funding

Psychosocial Influences on Rural Children's Oral HealthR01DE014899 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FOXMAN, BETSY, MARAZITA, MARY L. · 2002 to 2020
$39.9M
TRANSLATION MODULEP50DA005605 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RIDENOUR, TY A · 1989 to 2014
$25.7M
Fluoride & Other Factors in Childhood and Adolescent Bone DevelopmentR01DE012101 · NIDCR · UNIVERSITY OF IOWA · PI LEVY, STEVEN M. · 1998 to 2013
$11.9M
Genetic Epidemiology of Complex TraitsZIAHG200327 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BAILEY-WILSON, JOAN ELLEN · 2009 to 2022
$10.5M
LONGITUDINAL STUDY OF FLUORIDE EXPOSURES &FLUORIDER01DE009551 · NIDCR · UNIVERSITY OF IOWA · PI LEVY, STEVEN M. · 1991 to 2008
$4.7M
Genetics of CariesR01DE018914 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VIEIRA, ALEXANDRE REZENDE · 2009 to 2013
$2.2M
Substance Use Disorder Liability: Candidate Gene SystemR01DA019157 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VANYUKOV, MICHAEL M · 2004 to 2008
$2.2M
Dental Caries: Whole Genome Association and Gene x Environment StudiesU01DE018903 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MARAZITA, MARY L. · 2007 to 2010
$1.2M
Modeling childhood dental caries patterns for genomic and epigenetic analysisR03DE024264 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHAFFER, JOHN R · 2015 to 2016
$462k
NIDA NIH HHS P50 DA005605NIDA NIH HHS R01 DA019157NIDCR NIH HHS R01 DE009551NIDCR NIH HHS R01 DE012101NIDCR NIH HHS R01 DE014899NIDCR NIH HHS R01 DE018914NIDCR NIH HHS R03 DE024264NIDCR NIH HHS U01 DE018903
6 · The paper itself

Abstract

Matrix metalloproteinases (MMPs), which degrade extracellular proteins as part of a variety of physiological processes, and their inhibitors have been implicated in the dental caries process. Here we investigated 28 genetic variants spanning the

Identifiers

PMID28348596
PMCPMC5350286
OpenAlexW2593243297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.