Evidence map›Paper›PMID 28348568›Full record

ArticleFrontiers in immunology2017

A Bacterial Artificial Chromosome Reporter System for Expression of the Human

Masato Tsuda, Yukiko Tone, Chihiro Ogawa, Yoshiko Nagaoka, Makoto Katsumata, Andra Necula, Duncan Howie, Esteban Masuda, Herman Waldmann, Masahide Tone

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Masato TsudaDepartment of Biomedical Sciences, Cedars-Sinai Medical Center , Los Angeles, CA , USA.
Yukiko ToneDepartment of Biomedical Sciences, Cedars-Sinai Medical Center , Los Angeles, CA , USA.
Chihiro OgawaDepartment of Biomedical Sciences, Cedars-Sinai Medical Center , Los Angeles, CA , USA.
Yoshiko NagaokaDepartment of Biomedical Sciences, Cedars-Sinai Medical Center , Los Angeles, CA , USA.
Makoto KatsumataDepartment of Biomedical Sciences, Cedars-Sinai Medical Center , Los Angeles, CA , USA.
Andra NeculaSir William Dunn School of Pathology, University of Oxford , Oxford , UK.
Duncan HowieSir William Dunn School of Pathology, University of Oxford , Oxford , UK.
Esteban MasudaRigel Pharmaceuticals , South San Francisco, CA , USA.
Herman WaldmannSir William Dunn School of Pathology, University of Oxford , Oxford , UK.
Masahide ToneDepartment of Biomedical Sciences, Cedars-Sinai Medical Center , Los Angeles, CA , USA.
Cedars-Sinai Medical Center · USUniversity of Oxford · GBRigel (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transcription factor FOXP3 plays key roles in the development and function of regulatory T cells (Treg) capable of preventing and correcting immunopathology. There has been much interest in exploiting Treg as adoptive cell therapy in man, but issues of lack of nominal antigen-specificity and stability of FoxP3 expression in the face of pro-inflammatory cytokines have been a concern. In order to enable fundamental studies of human

Indexed as

bacterial artificial chromosomeFOXP3gene expressionregulatory T cellstranscription factor

Identifiers

PMID28348568
PMCPMC5346934
OpenAlexW2595073171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.