Evidence map›Paper›PMID 28348464›Full record

ArticleJournal of clinical and experimental hepatology2017

Liver Function Tests Abnormalities and Hepatitis B Virus & Hepatitis C Virus Co-infection in Human Immunodeficiency Virus (HIV)-infected Patients in India.

P Puri, P K Sharma, A Lolusare, V K Sashindran, S Shrivastava, A K Nagpal

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical and experimental hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

P PuriDepartment of Internal Medicine, Armed Forces Medical College, Pune 411040, India.
P K SharmaDepartment of Internal Medicine, Armed Forces Medical College, Pune 411040, India.
A LolusareDepartment of Gastroenterology, Army Hospital (R&R), New Delhi 110010, India.
V K SashindranDepartment of Internal Medicine, Armed Forces Medical College, Pune 411040, India.
S ShrivastavaDepartment of Gastroenterology, Command Hospital, Udhampur, India.
A K NagpalDepartment of Internal Medicine, Armed Forces Medical College, Pune 411040, India.
Armed Forces Medical College · INArmy Hospital Research and Referral · INCommand Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile highly active anti-retroviral therapy (HAART) has improved survival of HIV-infected patients, there is increasing liver disease and progressive Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) related liver disease.

aimsTo study the liver function tests (LFT) and HBV and HCV co-infection in HIV-infected patients. MATERIAL AND

methodsAll HIV-positive patients presenting to a tertiary level hospital from April 2009 to April 2011 were evaluated. Baseline LFT, CD4/CD8 counts, ultrasound abdomen, HBsAg, IgG anti-HBc, HBVDNA, Anti-HCV and HCVRNA were done in all patients. LFT was repeated monthly or more frequently with anti-tubercular therapy (ATT)/HAART.

resultsAbnormal LFT were seen in 143/320 (44.6%) HIV-infected patients (

conclusionWhile LFT abnormalities in HIV are common, they are usually mild and multifactorial. HBV and HCV co-infections were seen in 11.6% and 8.8%, respectively. Occult HBV and HCV infections were rare.

Indexed as

ATTHAARTHIV infectionLFT abnormalitiesviral hepatitis

Identifiers

PMID28348464
PMCPMC5357744
OpenAlexW2567154966

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.