Evidence map›Paper›PMID 28348449›Full record

ArticleDisease markers2017

Combined Genetic Biomarkers Confer Susceptibility to Risk of Urothelial Bladder Carcinoma in a Saudi Population.

Nasser Attia Elhawary, Anmar Nassir, Hesham Saada, Anas Dannoun, Omar Qoqandi, Ammar Alsharif, Mohammed Taher Tayeb

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease markers, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Impact of Long Non-Coding RNAJournal of clinical medicine · 2019
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Nasser Attia ElhawaryDepartment of Medical Genetics, Faculty of Medicine, Umm Al-Qura University, P.O. Box 57543, Mecca 21955, Saudi Arabia; Department of Molecular Genetics, Medical Genetics Center, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt.ORCID 0000-0002-9137-351X
Anmar NassirDepartment of Surgery, Faculty of Medicine, Umm Al-Qura University, Mecca 21955, Saudi Arabia; Department of Urology, King Abdullah Medical City Specialist Hospital, Mecca 21955, Saudi Arabia.
Hesham SaadaDepartment of Urology, King Abdullah Medical City Specialist Hospital, Mecca 21955, Saudi Arabia.
Anas DannounDepartment of Medical Genetics, Faculty of Medicine, Umm Al-Qura University, P.O. Box 57543, Mecca 21955, Saudi Arabia.
Omar QoqandiDepartment of Medical Genetics, Faculty of Medicine, Umm Al-Qura University, P.O. Box 57543, Mecca 21955, Saudi Arabia.
Ammar AlsharifDivision of Internal Medicine, Al-Noor Specialist Hospital, Mecca 21955, Saudi Arabia.
Mohammed Taher TayebDepartment of Medical Genetics, Faculty of Medicine, Umm Al-Qura University, P.O. Box 57543, Mecca 21955, Saudi Arabia.
Umm al-Qura University · SAAin Shams University · EGKing Abdullah Medical City · SASaad Specialist Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated the associations between seven single nucleotide polymorphisms and susceptibility to urothelial bladder carcinoma (UBC) in a Saudi population. Genomic DNA was taken from buccal cells of 52 patients with UBC and 104 controls for genotyping of GSTT1, GSTM1, rs4646903, rs1048943, TP53 rs1042522, rs1801133, and rs1801394 using PCR and TaqMan® assays. The rs1801133 and rs1801394 variants showed strong associations with UBC (OR = 2.3,

Indexed as

Polymorphism, Single NucleotideAgedAged, 80 and overBiomarkers, TumorCarcinomaCase-Control StudiesFemaleGenetic Predisposition to DiseaseGenotypeGlutathione TransferaseHomozygoteHumansMaleMiddle AgedSaudi ArabiaTumor Suppressor Protein p53Biomarkers, Tumorglutathione S-transferase T1Glutathione TransferaseTP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID28348449
PMCPMC5350417
OpenAlexW2593042226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.