Evidence map›Paper›PMID 28348229›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Structural basis of mitochondrial dysfunction in response to cytochrome

Blas Moreno-Beltrán, Alejandra Guerra-Castellano, Antonio Díaz-Quintana, Rebecca Del Conte, Sofía M García-Mauriño, Sofía Díaz-Moreno, Katiuska González-Arzola, Carlos Santos-Ocaña, Adrián Velázquez-Campoy, Miguel A De la Rosa and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 66 citations in OpenAlex.

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  13. Mitochondrial Factors in the Cell Nucleus.International journal of molecular sciences · 2023
    Review
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  17. De novo sequencing and construction of a unique antibody for the recognition of alternative conformations of cytochromeProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Blas Moreno-BeltránInstituto de Investigaciones Químicas, cicCartuja, Universidad de Sevilla-Spanish National Scientific Council (CSIC), 41092 Seville, Spain.
Alejandra Guerra-CastellanoInstituto de Investigaciones Químicas, cicCartuja, Universidad de Sevilla-Spanish National Scientific Council (CSIC), 41092 Seville, Spain.
Antonio Díaz-QuintanaInstituto de Investigaciones Químicas, cicCartuja, Universidad de Sevilla-Spanish National Scientific Council (CSIC), 41092 Seville, Spain.ORCID 0000-0001-8973-8009
Rebecca Del ConteMagnetic Resonance Center (CERM), Department of Chemistry, University of Florence, 50019 Sesto Fiorentino, Florence, Italy.
Sofía M García-MauriñoInstituto de Investigaciones Químicas, cicCartuja, Universidad de Sevilla-Spanish National Scientific Council (CSIC), 41092 Seville, Spain.
Sofía Díaz-MorenoDiamond Light Source, Didcot, Oxfordshire OX11 0DE, United Kingdom.
Katiuska González-ArzolaInstituto de Investigaciones Químicas, cicCartuja, Universidad de Sevilla-Spanish National Scientific Council (CSIC), 41092 Seville, Spain.
Carlos Santos-OcañaCentro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide-CSIC, 41013 Seville, Spain.
Adrián Velázquez-CampoyInstitute of Biocomputation and Physics of Complex Systems (BIFI), Joint Unit BIFI-Instituto Química-Física Rocasolano (CSIC), Universidad de Zaragoza, 50018 Zaragoza, Spain.
Miguel A De la RosaInstituto de Investigaciones Químicas, cicCartuja, Universidad de Sevilla-Spanish National Scientific Council (CSIC), 41092 Seville, Spain.
Paola TuranoMagnetic Resonance Center (CERM), Department of Chemistry, University of Florence, 50019 Sesto Fiorentino, Florence, Italy.
Irene Díaz-MorenoInstituto de Investigaciones Químicas, cicCartuja, Universidad de Sevilla-Spanish National Scientific Council (CSIC), 41092 Seville, Spain; idiazmoreno@us.es.
Centro de Investigaciones Científicas Isla de la Cartuja · ESInteruniversity Consortium for Magnetic Resonance · ITCentro Andaluz de Biología del Desarrollo · ESDiamond Light Source · GBUniversidad de Zaragoza · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulation of mitochondrial activity allows cells to adapt to changing conditions and to control oxidative stress, and its dysfunction can lead to hypoxia-dependent pathologies such as ischemia and cancer. Although cytochrome

Indexed as

Oxidative StressCytochromes cHumansMagnetic Resonance SpectroscopyMitochondriaMutationPeroxidasesPhenylalaninePhosphorylationProtein ConformationReactive Oxygen SpeciesSignal TransductionTyrosine4-carboxymethylphenylalanineCytochromes cPeroxidasesPhenylalanineReactive Oxygen SpeciesTyrosinecytochrome cmitochondrial dysfunctionnuclear magnetic resonancephosphorylationrespiratory supercomplexes

Identifiers

PMID28348229
PMCPMC5393209
OpenAlexW2603025173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.