Evidence map›Paper›PMID 28348214›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Spemann organizer transcriptome induction by early beta-catenin, Wnt, Nodal, and Siamois signals in

Yi Ding, Diego Ploper, Eric A Sosa, Gabriele Colozza, Yuki Moriyama, Maria D J Benitez, Kelvin Zhang, Daria Merkurjev, Edward M De Robertis

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Double assurance in the induction of axial development by egg dorsal determinants inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Molecular analysis of a self-organizing signaling pathway forProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. Cell lineage-guided mass spectrometry reveals increased energy metabolism and reactive oxygen species in the vertebrate organizer.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Genome Editing and Myocardial Development.Advances in experimental medicine and biology · 2023
    Review
  11. The Organizer and Its Signaling in Embryonic Development.Journal of developmental biology · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development inProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  16. Article
  17. Review
  18. BMP Signaling: Lighting up the Way for Embryonic Dorsoventral Patterning.Frontiers in cell and developmental biology · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yi DingHoward Hughes Medical Institute, University of California, Los Angeles, CA 90095-1662.
Diego PloperHoward Hughes Medical Institute, University of California, Los Angeles, CA 90095-1662.
Eric A SosaHoward Hughes Medical Institute, University of California, Los Angeles, CA 90095-1662.
Gabriele ColozzaHoward Hughes Medical Institute, University of California, Los Angeles, CA 90095-1662.
Yuki MoriyamaHoward Hughes Medical Institute, University of California, Los Angeles, CA 90095-1662.
Maria D J BenitezHoward Hughes Medical Institute, University of California, Los Angeles, CA 90095-1662.
Kelvin ZhangHoward Hughes Medical Institute, University of California, Los Angeles, CA 90095-1662.
Daria MerkurjevDepartment of Medicine, University of California, Los Angeles, CA 90095-1662.
Edward M De RobertisHoward Hughes Medical Institute, University of California, Los Angeles, CA 90095-1662; ederobertis@mednet.ucla.edu.
Howard Hughes Medical Institute · USUniversity of California, Los Angeles · US

Funding

MARC U*STAR Program at the University of California, Los AngelesT34GM008563 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCEVOY, MEGAN M, POE, GINA R · 1996 to 2023
$9.7M
UCLA MSD ProgramR25GM055052 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BARBER, PAUL HENRY, HASSON, TAMA W. · 1996 to 2021
$9.2M
Howard Hughes Medical InstituteNIGMS NIH HHS R25 GM055052NIGMS NIH HHS T34 GM008563
6 · The paper itself

Abstract

The earliest event in

Indexed as

Gene Expression Regulation, DevelopmentalTranscriptomeAmino Acid SequenceAnimalsbeta CateninHomeodomain ProteinsNodal ProteinOrganizers, EmbryonicSequence HomologyWnt ProteinsXenopus laevisXenopus Proteinsbeta CateninHomeodomain ProteinsNodal ProteinSIA1 protein, XenopusWnt ProteinsXenopus ProteinsCerberusembryonic inductionembryonic patterningSpemann organizerWnt signaling

Identifiers

PMID28348214
PMCPMC5393196
OpenAlexW2600314451

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.