Evidence map›Paper›PMID 28348196›Full record

Observational studyBMJ open2017

Secondary prevention and cognitive function after stroke: a study protocol for a 5-year follow-up of the ASPIRE-S cohort.

Daniela Rohde, David Williams, Eva Gaynor, Kathleen Bennett, Eamon Dolan, Elizabeth Callaly, Margaret Large, Anne Hickey

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Daniela RohdeDivision of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.ORCID 0000-0001-8834-2539
David WilliamsDepartment of Geriatric and Stroke Medicine, Royal College of Surgeons in Ireland and Beaumont Hospital, Dublin, Ireland.
Eva GaynorDepartment of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Kathleen BennettDivision of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
Eamon DolanDepartment of Geriatric Medicine, Connolly Hospital Blanchardstown, Dublin, Ireland.
Elizabeth CallalyDepartment of Geriatric Medicine, Mater Misericordiae University Hospital, Dublin, Ireland.
Margaret LargeClinical Research Centre, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland.
Anne HickeyDivision of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
Royal College of Surgeons in Ireland · IEConnolly Hospital Blanchardstown · IEMater Misericordiae University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCognitive impairment is common following stroke and can increase disability and levels of dependency of patients, potentially leading to greater burden on carers and the healthcare system. Effective cardiovascular risk factor control through secondary preventive medications may reduce the risk of cognitive decline. However, adherence to medications is often poor and can be adversely affected by cognitive deficits. Suboptimal medication adherence negatively impacts secondary prevention targets, increasing the risk of recurrent stroke and further cognitive decline. The aim of this study is to profile cognitive function and secondary prevention, including adherence to secondary preventive medications and healthcare usage, 5 years post-stroke. The prospective associations between cognition, cardiovascular risk factors, adherence to secondary preventive medications, and rates of recurrent stroke or other cardiovascular events will also be explored. METHODS AND ANALYSIS: This is a 5-year follow-up of a prospective study of the Action on Secondary Prevention Interventions and Rehabilitation in Stroke (ASPIRE-S) cohort of patients with stroke. This cohort will have a detailed assessment of cognitive function, adherence to secondary preventive medications and cardiovascular risk factor control. ETHICS AND DISSEMINATION: Ethical approval for this study was granted by the Research Ethics Committees at Beaumont Hospital, Dublin and Connolly Hospital, Dublin, Mater Misericordiae University Hospital, Dublin, and the Royal College of Surgeons in Ireland. Findings will be disseminated through presentations and peer-reviewed publications.

Indexed as

Drug MonitoringSecondary PreventionAgedAnticoagulantsAntihypertensive AgentsCardiovascular DiseasesCognition DisordersFemaleFollow-Up StudiesHumansIrelandMaleRisk FactorsStrokeStroke RehabilitationSurvivorsAnticoagulantsAntihypertensive Agentscardiovascular risk factorsmedication adherencesecondary prevention

Identifiers

PMID28348196
PMCPMC5372058
OpenAlexW2600559560

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.