Evidence map›Paper›PMID 28348176›Full record

ReviewCold Spring Harbor perspectives in medicine2017

Honing Cell and Tissue Culture Conditions for Bone and Cartilage Tissue Engineering.

Johnny Lam, Esther J Lee, Elisa C Clark, Antonios G Mikos

Open access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Tissue Engineering for Penile Reconstruction.Bioengineering (Basel, Switzerland) · 2024
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Johnny LamDepartment of Bioengineering, Rice University, Houston, Texas 77251.
Esther J LeeDepartment of Bioengineering, Rice University, Houston, Texas 77251.
Elisa C ClarkDepartment of Bioengineering, Rice University, Houston, Texas 77251.
Antonios G MikosDepartment of Chemical and Biomolecular Engineering, Rice University, Houston, Texas 77251.
Rice University · US

Funding

Injectable Cellular Composites for Cartilage EngineeringR01AR048756 · NIAMS · RICE UNIVERSITY · PI KASPER, FRED KURTIS, MIKOS, ANTONIOS G. · 2003 to 2014
$3.3M
In Situ Hardening Cell-Laden Constructs for Osteochondral Tissue EngineeringR01AR068073 · NIAMS · RICE UNIVERSITY · PI MIKOS, ANTONIOS G. · 2015 to 2019
$1.7M
An Optogenetic Approach to Bone Tissue EngineeringR21AR067527 · NIAMS · RICE UNIVERSITY · PI MIKOS, ANTONIOS G., TABOR, JEFFREY JAY · 2015 to 2016
$356k
NIAMS NIH HHS R01 AR048756NIAMS NIH HHS R01 AR068073NIAMS NIH HHS R21 AR067527
6 · The paper itself

Abstract

An avenue of tremendous interest and need in health care encompasses the regeneration of bone and cartilage. Over the years, numerous tissue engineering strategies have contributed substantial progress toward the realization of clinically relevant therapies. Cell and tissue culture protocols, however, show many variations that make experimental results among different publications challenging to compare. This collection surveys prevalent cell sources, soluble factors, culture medium formulations, environmental factors, and genetic modification approaches in the literature. The intent of consolidating this information is to provide a starting resource for scientists considering how to optimize the parameters for cell differentiation and tissue culture procedures within the context of bone and cartilage tissue engineering.

Indexed as

RegenerationAnimalsBone and BonesCartilageCell Culture TechniquesCell DifferentiationHumansTissue Engineering

Identifiers

PMID28348176
PMCPMC5710100
OpenAlexW2602231905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.