Evidence map›Paper›PMID 28348159›Full record

ArticleAntimicrobial agents and chemotherapy2017

An Azole-Tolerant Endosomal Trafficking Mutant of Candida albicans Is Susceptible to Azole Treatment in a Mouse Model of Vaginal Candidiasis.

Brian M Peters, Arturo Luna-Tapia, Hélène Tournu, Jeffrey M Rybak, P David Rogers, Glen E Palmer

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Vacuolar CamSphere · 2019
    Article
  5. Bioactive Peptides Against Fungal Biofilms.Frontiers in microbiology · 2019
    Review
  6. Loss of C-5 Sterol Desaturase Activity inAntimicrobial agents and chemotherapy · 2019
    Article
  7. Article
  8. Methodologies forMicrobial cell (Graz, Austria) · 2018
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Brian M PetersDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Arturo Luna-TapiaDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Hélène TournuDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Jeffrey M RybakDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
P David RogersDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Glen E PalmerDepartment of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA gpalmer5@uthsc.edu.
University of Tennessee Health Science Center · USLouisiana State University Health Sciences Center New Orleans · US

Funding

Novel Azole Resistance Mechanisms in Candida albicansR01AI058145 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ROGERS, P. DAVID · 2005 to 2021
$5.8M
Molecular and chemical validation of the vacuole as a new antifungal targetR01AI099080 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI PALMER, GLEN · 2014 to 2018
$1.9M
A novel role for the inflammasome in the immunopathogenesis of Candida vaginitisK22AI110541 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI PETERS, BRIAN M · 2016 to 2017
$268k
NIAID NIH HHS K22 AI110541NIAID NIH HHS R01 AI058145NIAID NIH HHS R01 AI099080
6 · The paper itself

Abstract

We recently reported that a

Indexed as

AnimalsAntifungal AgentsCandida albicansCandidiasis, VulvovaginalDisease Models, AnimalDrug Resistance, FungalFemaleFluconazoleMembrane Transport ProteinsMiceMice, Inbred C57BLMicrobial Sensitivity Testsrab GTP-Binding ProteinsAntifungal AgentsFluconazoleMembrane Transport Proteinsrab GTP-Binding ProteinsazolesCandida albicansresistancetolerancevaginal candidiasisVps21p

Identifiers

PMID28348159
PMCPMC5444139
OpenAlexW2602359364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.