Evidence map›Paper›PMID 28348065›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Genomic Disorders and Neurocognitive Impairment in Pediatric CKD.

Miguel Verbitsky, Amy J Kogon, Matthew Matheson, Stephen R Hooper, Craig S Wong, Bradley A Warady, Susan L Furth, Ali G Gharavi

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00327860 (Chronic Kidney Disease in Children Prospective Cohort Study), which is not on this map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00327860 recruitingnot on this map

Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)

TypeobservationalSponsorJohns Hopkins Bloomberg School of Public HealthRan2003 to 2028Enrolled1,300ConditionsChronic Kidney Disease
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Autism spectrum disorder and kidney disease.Pediatric nephrology (Berlin, Germany) · 2021
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Mechanisms of cognitive dysfunction in CKD.Nature reviews. Nephrology · 2020
    Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

Miguel VerbitskyDivision of Nephrology, College of Physicians and Surgeons, Columbia University, New York, New York.
Amy J KogonDivision of Pediatric Nephrology, Nationwide Children's Hospital, Columbus, Ohio.
Matthew MathesonDepartment of Epidemiology, Johns Hopkins University, Baltimore, Maryland; Departments of.
Stephen R HooperAllied Health Sciences and.
Craig S WongDivision of Pediatric Nephrology, University of New Mexico Children's Hospital, Albuquerque, New Mexico.
Bradley A WaradyDivision of Pediatric Nephrology, Children's Mercy Hospital, Kansas City, Missouri; Departments of.
Susan L FurthPediatrics and.
Ali G GharaviDivision of Nephrology, College of Physicians and Surgeons, Columbia University, New York, New York; ag2239@columbia.edu.
Columbia University · USChildren's Hospital of Philadelphia · USChildren's Mercy Hospital · USJohns Hopkins University · USNationwide Children's Hospital · USUniversity of North Carolina at Chapel Hill · USUNM Children's Hospital · US

Funding

Chronic Kidney Disease in Children Study (C-Kid)U01DK066174 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SUSAN L. FURTH · 2003 to 2026
$25.1M
CKiD Cardiovascular Testing Travel SupplementU01DK066143 · NIDDK · CHILDREN'S MERCY HOSP (KANSAS CITY, MO) · PI Bradley Alan Warady · 2003 to 2026
$24.2M
The Kidney Disease in Children Data Management and Analysis Center (KIDMAC)U01DK066116 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MUNOZ, ALVARO · 2003 to 2017
$17.9M
Transcriptional Regulation of Urothelial Differentiation During Homeostasis and Repair in Response to Urinary Tract InfectionU54DK104309 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI JONATHAN M. BARASCH, ALI G GHARAVI · 2014 to 2026
$17.7M
Translational Neuroscience CoreU54HD079123 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI FATEMI, S. ALI, SCHLAGGAR, BRADLEY L · 2014 to 2019
$7.9M
Genetics of Renal HypodyslasiaR01DK080099 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GHARAVI, ALI G · 2008 to 2023
$6.3M
Central Biochemistry Laboratory of the CKiD ConsortiumU01DK082194 · NIDDK · UNIVERSITY OF ROCHESTER · PI SCHWARTZ, GEORGE J · 2008 to 2017
$3.5M
Pediatric investigation for genetic factors linked to renal progression (PediGFR)R01DK082394 · NIDDK · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI WONG, CRAIG S. · 2010 to 2013
$2.2M
NICHD NIH HHS U54 HD079123NIDDK NIH HHS R01 DK080099NIDDK NIH HHS R01 DK082394NIDDK NIH HHS U01 DK066116NIDDK NIH HHS U01 DK066143NIDDK NIH HHS U01 DK066174NIDDK NIH HHS U01 DK082194NIDDK NIH HHS U54 DK104309
6 · The paper itself

Abstract

Children with CKD are at increased risk for neurocognitive impairment, but whether neurocognitive dysfunction is solely attributable to impaired renal function is unclear. Data from the CKD in Children Study Chronic Kidney Disease in Children (CKiD) Study indicate that a subset of children with CKD have unsuspected genomic disorders that predispose them to organ malformations and neurocognitive impairment. We therefore tested whether the CKiD Study participants with genomic disorders had impaired neurocognitive performance at enrollment. Compared with noncarriers (

Indexed as

ChildCognitive DysfunctionFemaleGenetic Diseases, InbornGenomicsHumansMaleNervous System DiseasesRenal Insufficiency, Chronicchronic kidney diseaseEpidemiology and outcomeshuman geneticspediatric nephrology

Identifiers

PMID28348065
PMCPMC5533237
OpenAlexW2597782064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.