Evidence map›Paper›PMID 28348056›Full record

ArticleInfection and immunity2017

Analysis of Shigella flexneri Resistance, Biofilm Formation, and Transcriptional Profile in Response to Bile Salts.

Kourtney P Nickerson, Rachael B Chanin, Jeticia R Sistrunk, David A Rasko, Peter J Fink, Eileen M Barry, James P Nataro, Christina S Faherty

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 2 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 2 syntheses or guidelines pooled it, 105 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. bioRxiv : the preprint server for biology · 2026
    Article
  5. Multidrug-ResistantPolish journal of microbiology · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Microbial genomics · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kourtney P NickersonMucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Rachael B ChaninMucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Jeticia R SistrunkInstitute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
David A RaskoInstitute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID http://orcid.org/0000-0002-7337-7154
Peter J FinkMucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Eileen M BarryCenter for Vaccine Development, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
James P NataroDepartment of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Christina S FahertyMucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA csfaherty@partners.org.
Harvard University · USUniversity of Maryland, Baltimore · USUniversity of Virginia · US

Funding

Technology CoreU19AI110820 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI DUNNING HOTOPP, JULIE · 2014 to 2023
$36.5M
Signaling Pathways in Innate ImmunityT32AI095190 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Stefanie N. Vogel · 2012 to 2026
$4.7M
MGHfC Digestive Disease Summer Research ProgramR25DK103579 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI BRYAN P HURLEY · 2015 to 2026
$1.2M
The mechanism of Shigella flexneri adherence during the early infection processK22AI104755 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI FAHERTY, CHRISTINA S · 2014 to 2015
$270k
NIAID NIH HHS K22 AI104755NIAID NIH HHS T32 AI095190NIAID NIH HHS U19 AI110820NIDDK NIH HHS R25 DK103579
6 · The paper itself

Abstract

The

Indexed as

Bacterial ProteinsBile Acids and SaltsBiofilmsGene Expression ProfilingHeLa CellsHT29 CellsHumansMicroscopy, ElectronMutationO AntigensSequence Analysis, RNAShigella flexneriVirulenceBacterial ProteinsBile Acids and SaltsO Antigensbile saltsbiofilmEPS matrixEscherichia coliresistanceShigellavirulencevirulence genes

Identifiers

PMID28348056
PMCPMC5442615
OpenAlexW2600310887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.