Evidence map›Paper›PMID 28348006›Full record

ArticlePhysiological reports2017

GABA

Wen Shen, Changlong Nan, Peter T Nelson, Harris Ripps, Malcolm M Slaughter

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Ectopic activation of GABANature ecology & evolution · 2021
    Article
  4. Article
  5. Observational
  6. Enhanced Postsynaptic GABANeuroscience · 2018
    Article
  7. Article
  8. GABAPhysiological reports · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Wen ShenDepartment of Biomedical Science, Charles E. Schmidt College of Medicine Florida Atlantic University, Boca Raton, Florida wshen@fau.edu.
Changlong NanDepartment of Biomedical Science, Charles E. Schmidt College of Medicine Florida Atlantic University, Boca Raton, Florida.
Peter T NelsonDivision of Neuropathology, Department of Pathology, University of Kentucky, Lexington, Kentucky.
Harris RippsDepartment of Ophthalmology and Visual Sciences, University of Illinois College of Medicine, Chicago, Illinois.
Malcolm M SlaughterDepartment of Physiology and Biophysics, State University of New York at Buffalo, Buffalo, New York.
Florida Atlantic University · USIllinois College · USUniversity at Buffalo, State University of New York · USUniversity of Kentucky · US

Funding

Interplexiform Cell FunctionR01EY014161 · NEI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI SHEN, WEN · 2002 to 2005
$1.1M
NEI NIH HHS R01 EY014161
6 · The paper itself

Abstract

Ionotropic receptors are tightly regulated by second messenger systems and are often present along with their metabotropic counterparts on a neuron's plasma membrane. This leads to the hypothesis that the two receptor subtypes can interact, and indeed this has been observed in excitatory glutamate and inhibitory GABA receptors. In both systems the metabotropic pathway augments the ionotropic receptor response. However, we have found that the metabotropic GABA

Indexed as

Action PotentialsAnimalsFemaleHumansMaleMiceNeuronsPatch-Clamp TechniquesReceptors, GABA-AReceptors, GABA-BRetinal Ganglion CellsXenopusReceptors, GABA-AReceptors, GABA-BGABAA receptorsGABAB receptorshuman amygdalamouse retinaρ‐subunit GABAA receptors

Identifiers

PMID28348006
PMCPMC5371550
OpenAlexW2600034123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.