Evidence map›Paper›PMID 28347326›Full record

ArticleParasites & vectors2017

First report of the Phe1534Cys kdr mutation in natural populations of Aedes albopictus from Brazil.

Oscar Alexander Aguirre-Obando, Ademir Jesus Martins, Mário Antônio Navarro-Silva

RetractedAbstract readRetracted Publication
In one paragraph

Article in Parasites & vectors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Knockdown Resistance (Frontiers in cellular and infection microbiology · 2021
    Article
  8. Vector Competence ofPathogens (Basel, Switzerland) · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. First detection of aEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Oscar Alexander Aguirre-ObandoLaboratório de Entomologia Médica e Veterinária, Setor de Ciências Biológicas, Departamento de Zoologia, Universidade Federal do Paraná, PO Box 19020, Curitiba, 81531-980, Paraná, Brazil.
Ademir Jesus MartinsLaboratório de Fisiologia e Controle de Artrópodes Vetores, Instituto Oswaldo Cruz-FIOCRUZ, Av. Brasil 4365, Rio de Janeiro-RJ, PO Box 2104-900, Brazil. ademirjr@ioc.fiocruz.br.
Mário Antônio Navarro-SilvaLaboratório de Entomologia Médica e Veterinária, Setor de Ciências Biológicas, Departamento de Zoologia, Universidade Federal do Paraná, PO Box 19020, Curitiba, 81531-980, Paraná, Brazil.

Funding

Genetic Studies of Dengue Vectors in BrazilU01AI115595 · NIAID · YALE UNIVERSITY · PI POWELL, JEFFREY R · 2015 to 2019
$3.6M
NIAID NIH HHS U01 AI115595
6 · The paper itself

Abstract

backgroundKnockdown resistance (kdr), caused by alterations in the voltage-gated sodium channel (Na

methodsDNA from eight Brazilian Ae. albopictus natural populations were individually extracted and pooled by states of origin, amplified, cloned and sequenced for the corresponding IIS6 and IIIS6 Na

resultsNo non-synonymous substitutions were observed in the IIS6 sequences. However, the Phe1534Cys kdr mutation was evidenced in the Ae. albopictus Na

conclusionThe emergence of a likely kdr mutation in Ae. albopitus natural populations is a signal of alert for vector control measures since PY are the most popular insecticides adopted by residents. Additionally, once the kdr allele is present, its frequency tends to increase faster under exposition to those compounds. Although the Asian tiger mosquito is not incriminated as an important vector of dengue, chikungunya and Zika viruses in South America, its importance in this regard has been extensively discussed since Ae. albopictus is rapidly spreading and can also migrate between sylvatic and urban environments. Therefore, insecticide resistance monitoring initiatives should also be extended to Ae. albopictus in Brazil in order to maintain chemical compounds as an efficient vector control tool when needed.

Indexed as

Genes, InsectMutationAedesAllelesAnimalsAsiaBrazilChikungunya FeverDengueDNAEuropeGene FrequencyGenotypeInsecticide ResistanceMosquito VectorsNorth AmericaDNAPyrethrinsAllele-specific PCRChikungunyaDenguePyrethroid resistanceVector controlVoltage-gated sodium channelZika

Identifiers

PMID28347326
PMCPMC5369189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.