Evidence map›Paper›PMID 28347282›Full record

ArticleBMC nephrology2017

Hyperuricemia after orthotopic liver transplantation: divergent associations with progression of renal disease, incident end-stage renal disease, and mortality.

Joseph C Longenecker, Sana Waheed, Ghassan Bandak, Christine A Murakami, Blaithin A McMahon, Allan C Gelber, Mohamed G Atta

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Complications in Post-Liver Transplant Patients.Journal of clinical medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Joseph C LongeneckerDepartment of Community Medicine and Behavioural Sciences, Kuwait University Faculty of Medicine, Kuwait City, Kuwait.
Sana WaheedDepartment of Medicine, University of Wisconsin School of Medicine, Madison, WI, USA.
Ghassan BandakDepartment of Medicine, Mayo Clinic, Rochester, MN, USA.
Christine A MurakamiLakelands Nephrology, PA, Greenwood, SC, USA.
Blaithin A McMahonDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Allan C GelberDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mohamed G AttaDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. matta1@jhmi.edu.
Johns Hopkins Medicine · USJohns Hopkins University · USMayo Clinic in Arizona · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough hyperuricemia is common after orthotopic liver transplantation (OLT), its relationship to mortality, progressive kidney disease, or the development of end stage renal disease (ESRD) is not well-described.

methodsData from 304 patients undergoing OLT between 1996 and 2010 were used to assess the association of mean serum uric acid (UA) level in the 3-months post-OLT with mortality, doubling of creatinine, and ESRD incidence. Post-OLT survival to event outcomes according to UA level and eGFR was assessed using the Kaplan Meier method and multivariate Cox proportional hazards models.

resultsMean UA level among the 204 patients with an eGFR level ≥60 ml/min/1.73 m

conclusionIn this post-OLT cohort, hyperuricemia independently predicted mortality, particularly among patients with eGFR < 60, and predicted doubling of creatinine among diabetics.

Indexed as

Liver TransplantationMortalityAdultCreatinineDisease ProgressionFemaleGlomerular Filtration RateHumansHyperuricemiaIncidenceKaplan-Meier EstimateKidney Failure, ChronicLiver FailureMaleMiddle AgedMultivariate AnalysisCreatinineUric AcidClinical epidemiologyeGFRLiver transplantationUric acid

Identifiers

PMID28347282
PMCPMC5369182
OpenAlexW2602188939

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.