Evidence map›Paper›PMID 28347072›Full record

ArticleNanomaterials (Basel, Switzerland)2015

Comparison of the

Oana T Marisca, Karsten Kantner, Christian Pfeiffer, Qian Zhang, Beatriz Pelaz, Nicolae Leopold, Wolfgang J Parak, Joanna Rejman

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Oana T MariscaFachbereich Physik, Philipps Universität Marburg, Marburg 35037, Germany. nicolae.leopold@phys.ubbcluj.ro.
Karsten KantnerFachbereich Physik, Philipps Universität Marburg, Marburg 35037, Germany. kantnerk@staff.uni-marburg.de.
Christian PfeifferFachbereich Physik, Philipps Universität Marburg, Marburg 35037, Germany. pfeiffer-christian@gmx.net.
Qian ZhangFachbereich Physik, Philipps Universität Marburg, Marburg 35037, Germany. qian.zhang@physik.uni-marburg.de.
Beatriz PelazFachbereich Physik, Philipps Universität Marburg, Marburg 35037, Germany. beatriz.pelazgarcia@physik.uni-marburg.de.
Nicolae LeopoldFaculty of Physics, Babeş-Bolyai University, Cluj-Napoca 400084, Romania. nicolae.leopold@phys.ubbcluj.ro.
Wolfgang J ParakFachbereich Physik, Philipps Universität Marburg, Marburg 35037, Germany. wolfgang.parak@physik.uni-marburg.de.
Joanna RejmanFachbereich Physik, Philipps Universität Marburg, Marburg 35037, Germany. joanna.rejman@med.uni-muenchen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the physico-chemical properties (size, shape, zeta-potential), cellular internalization and toxicity of gold nanoparticles (NPs) stabilized with the most abundant mammalian protein, collagen. The properties of these gold NPs were compared to the same sized gold NPs coated with synthetic poly(isobutylene-alt-maleic anhydride) (PMA). Intracellular uptake and cytotoxicity were assessed in two cell lines (cervical carcinoma and lung adenocarcinoma cells) by employing inductively-coupled plasma-mass spectrometry (ICP-MS) analysis and a cell viability assay based on 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), respectively. We found that the collagen-coated gold NPs exhibit lower cytotoxicity, but higher uptake levels than PMA-coated gold NPs. These results demonstrate that the surface coating of Au NPs plays a decisive role in their biocompatibility.

Indexed as

biocompatibilitycellular uptakegold nanoparticlestoxicity

Identifiers

PMID28347072
PMCPMC5304636

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.