Evidence map›Paper›PMID 28347052›Full record

ArticleNanomaterials (Basel, Switzerland)2015

Examination of Single-Walled Carbon Nanotubes Uptake and Toxicity from Dietary Exposure: Tracking Movement and Impacts in the Gastrointestinal System.

Joseph H Bisesi, Thuy Ngo, Satvika Ponnavolu, Keira Liu, Candice M Lavelle, A R M Nabiul Afrooz, Navid B Saleh, P Lee Ferguson, Nancy D Denslow, Tara Sabo-Attwood

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
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  9. Di- and tripeptide transport in vertebrates: the contribution of teleost fish models.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2017
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Joseph H BisesiDepartment of Environmental and Global Health, Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL 32611, USA. jbisesi@phhp.ufl.edu.
Thuy NgoDepartment of Environmental and Global Health, Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL 32611, USA. tweetiebird@ufl.edu.
Satvika PonnavoluDepartment of Environmental and Global Health, Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL 32611, USA. sponnavolu@ufl.edu.
Keira LiuDepartment of Civil and Environmental Engineering, Nicholas School of the Environment, Duke University, Durham, NC 27708, USA. keira.liu@duke.edu.
Candice M LavelleDepartment of Environmental and Global Health, Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL 32611, USA. ndenslow@ufl.edu.
A R M Nabiul AfroozDepartment of Civil, Architectural, and Environmental Engineering, The University of Texas Austin, Austin, TX 78712, USA. afrooz@utexas.edu.
Navid B SalehDepartment of Civil, Architectural, and Environmental Engineering, The University of Texas Austin, Austin, TX 78712, USA. navid.saleh@utexas.edu.
P Lee FergusonDepartment of Civil and Environmental Engineering, Nicholas School of the Environment, Duke University, Durham, NC 27708, USA. lee.ferguson@duke.edu.
Nancy D DenslowDepartment of Physiological Sciences, Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL 32611, USA. ndenslow@ufl.edu.
Tara Sabo-AttwoodDepartment of Environmental and Global Health, Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL 32611, USA. sabo@phhp.ufl.edu.
University of Florida · USDuke University · USThe University of Texas at Austin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies indicate that exposure of fish to pristine single-walled carbon nanotubes (SWCNTs) by oral gavage, causes no overt toxicity, and no appreciable absorption has been observed. However, in the environment, SWCNTs are likely to be present in dietary sources, which may result in differential impacts on uptake and biological effects. Additionally, the potential of these materials to sorb nutrients (proteins, carbohydrates, and lipids) while present in the gastrointestinal (GI) tract may lead to nutrient depletion conditions that impact processes such as growth and reproduction. To test this phenomenon, fathead minnows were fed a commercial diet either with or without SWCNTs for 96 h. Tracking and quantification of SWCNTs using near-infrared fluorescence (NIRF) imaging during feeding studies showed the presence of food does not facilitate transport of SWCNTs across the intestinal epithelia. Targeting genes shown to be responsive to nutrient depletion (peptide transporters, peptide hormones, and lipases) indicated that

Indexed as

fishgastrointestinal systemgene expressionnear-infrared fluorescence (NIRF)nutrient transporterssingle-walled carbon nanotubes(SWCNTs)sorption

Identifiers

PMID28347052
PMCPMC5312889
OpenAlexW1495563343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.