ArticleThe journal of nutrition, health & aging2017
Effectiveness of Cardiac Rehabilitation for Prevention and Treatment of Sarcopenia in Patients with Cardiovascular Disease - A Retrospective Cross-Sectional Analysis.
Article in The journal of nutrition, health & aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Pooled it
- The effect of protein and essential amino acid supplementation on muscle strength and performance in patients with chronic heart failure: a systematic review.European journal of nutrition · 2020Pooled it
- Effects of Different Exercise Interventions on Fall Risk and Gait Parameters in Frail Patients After Open Heart Surgery: A Pilot Study.Medicina (Kaunas, Lithuania) · 2025Trial
- Frailty and Different Exercise Interventions to Improve Gait Speed in Older Adults after Acute Coronary Syndrome.Medicina (Kaunas, Lithuania) · 2021Trial
- Study on nutritional status and incidence of sarcopenia in elderly patients with chronic heart failure.Asia Pacific journal of clinical nutrition · 2026Article
- Divergent effects of exercise training on peak oxygen uptake and 6-min walk distance in older HFpEF patients with and without type 2 diabetes mellitus.Heart and vessels · 2026Article
- Cardiac surgery as a means of reversing frailty - the CURE-Frailty Trial a prospective cohort study.BMC geriatrics · 2026Observational
- Impact of Sarcopenia and Nutritional Status on Survival of Patients with Aortic Dissection: A Scoping Review.Nutrients · 2025Article
- When the Heart, Kidneys, and Body Waste Away: A Review of Cachexia in Cardiorenal Syndrome.Current heart failure reports · 2025Review
- Early Effect of Supplementation with Essential Amino Acids on Cardiac Performance in Elderly Patients with Heart Failure and Sarcopenia.International journal of molecular sciences · 2025Observational
- Heart failure treatment and serum carnitines in HFpEF and HFrEF with or without hypertension - a pilot study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Article
- Effects of statins on sarcopenia with focus on mechanistic insights and future perspectives.Frontiers in pharmacology · 2025Review
- Review
- Provision of dietary education in UK-based cardiac rehabilitation: a cross-sectional survey conducted in conjunction with the British Association for Cardiovascular Prevention and Rehabilitation.The British journal of nutrition · 2024Article
- The prevalence and impact of sarcopenia in older cardiac patients undergoing inpatient cardiac rehabilitation - results from a prospective, observational cohort pre-study.BMC geriatrics · 2024Observational
- Feasibility of early digital health rehabilitation after cardiac surgery in the elderly: a qualitative study.BMC health services research · 2024Article
- Is sarcopenia an associated factor of increased administration of specific medications in patients with heart failure? A systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Review
- Sarcopenia and Cardiovascular Diseases.Circulation · 2023Review
- Barriers and Facilitators to Delivering Inpatient Cardiac Rehabilitation: A Scoping Review.Journal of multidisciplinary healthcare · 2023Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSarcopenia is a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength, with the risk of frailty and poor quality of life. This study aimed to clarify the clinical characteristics of sarcopenia and to investigate the effects of comprehensive cardiac rehabilitation (CCR), including nutrition, physical exercise and medication, in patients with cardiovascular disease (CVD).
methodsWe retrospectively studied 322 inpatients with CVD (age 72±12 years). Muscle mass, muscle strength and physical performance were assessed before and after exercise training in patients with and without sarcopenia, which was defined as either a gait speed of <0.8 m/s or reduced handgrip strength (<26 kg in males and <18 kg in females), together with lower skeletal muscle index (SMI) (<7.0 kg/m2 in males and <5.7 kg/m2 in females). The actual daily total calorie and nutrient intake was also calculated.
resultsSarcopenia was identified in 28% of patients with CVD, these patients having a higher prevalence of symptomatic chronic heart failure and chronic kidney disease. SMI was significantly associated with protein intake and statin treatment. The ratio of peak VO2 and SMI was significantly higher in the statin treatment group. Handgrip strength, gait speed, leg weight bearing index, and nutritional intake improved after exercise training in patients both with and without sarcopenia.
conclusionsThe present findings suggest that CCR is a promising strategy for prevention and treatment of sarcopenia in patients with CVD.
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