Evidence map›Paper›PMID 28346442›Full record

ArticleNature genetics2017

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

Catherine M Phelan, Karoline B Kuchenbaecker, Jonathan P Tyrer, Siddhartha P Kar, Kate Lawrenson, Stacey J Winham, Joe Dennis, Ailith Pirie, Marjorie J Riggan, Ganna Chornokur and 410 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 337 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
337citing papers in PubMed, 11 pooled it
80.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

337 citing papers in PubMed, 11 syntheses or guidelines pooled it, 542 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Predicted Proteome Association Studies of Breast, Prostate, Ovarian, and Endometrial Cancers Implicate Plasma Protein Regulation in Cancer Susceptibility.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Pooled it
  7. Pooled it
  8. Pooled it
  9. Investigation of Shared Genetic Risk Factors Between Parkinson's Disease and Cancers.Movement disorders : official journal of the Movement Disorder Society · 2023
    Pooled it
  10. Pooled it
  11. Pooled it
  12. Using Polygenic Risk Scores to Refine Risk and Outcomes in High-grade Serous Ovarian Cancer in Australia.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

277 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

420 authors at 20 institutions in 31 countries.

Catherine M PhelanDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA.
Karoline B KuchenbaeckerWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, UK.ORCID http://orcid.org/0000-0001-9726-603X
Jonathan P TyrerDepartment of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
Siddhartha P KarDepartment of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
Kate LawrensonWomen's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Stacey J WinhamDivision of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, Rochester, Minnesota, USA.
Joe DennisDepartment of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
Ailith PirieDepartment of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
Marjorie J RigganDepartment of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA.
Ganna ChornokurDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA.
Madalene A EarpDepartment of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, Minnesota, USA.
Paulo C LyraDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA.
Janet M LeeCenter for Bioinformatics and Functional Genomics, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Simon CoetzeeCenter for Bioinformatics and Functional Genomics, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Jonathan BeesleyDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Lesley McGuffogCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Penny SoucyGenomics Center, Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Quebec, Canada.
Ed DicksDepartment of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
Andrew LeeCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Daniel BarrowdaleCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Julie LecarpentierCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Goska LeslieCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Cora M AalfsDepartment of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands.
Katja K H AbenRadboud University Medical Center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, the Netherlands.
Marcia AdamsCenter for Inherited Disease Research, Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Julian AdlardYorkshire Regional Genetics Service, Chapel Allerton Hospital, Leeds, UK.
Irene L AndrulisLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Hoda Anton-CulverGenetic Epidemiology Research Institute, UCI Center for Cancer Genetics Research and Prevention, School of Medicine, University of California-Irvine, Irvine, California, USA.
Natalia AntonenkovaN.N. Alexandrov National Cancer Centre of Belarus, Minsk, Belarus.
AOCS study group
Gerasimos Aravantinos'Agii Anargiri' Cancer Hospital, Athens, Greece.
Norbert ArnoldDepartment of Gynaecology and Obstetrics, University Hospital of Schleswig-Holstein, Campus Kiel, Christian Albrechts University Kiel, Kiel, Germany.
Banu K ArunDepartment of Breast Medical Oncology and Clinical Cancer Genetics Program, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Brita ArverDepartment of Oncology and Pathology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.
Jacopo AzzolliniUnit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), Milan, Italy.
Judith BalmañaDepartment of Medical Oncology, University Hospital, Vall d'Hebron, Barcelona, Spain.
Susana N BanerjeeGynaecology Unit, Royal Marsden Hospital, London, UK.
Laure BarjhouxBâtiment Cheney D, Centre Léon Bérard, Lyon, France.
Rosa B BarkardottirLaboratory of Cell Biology, Department of Pathology, Landspitali, Reykjavik, Iceland.
Yukie BeanDepartment of Gynecologic Oncology, Oregon Health &Science University, Portland, Oregon, USA.
Matthias W BeckmannDepartment of Gynecology and Obstetrics, Universtiy Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-Nuremberg, Erlangen, Germany.
Alicia Beeghly-FadielDivision of Epidemiology, Department of Medicine, Vanderbilt School of Medicine, Nashville, Tennessee, USA.
Javier BenitezHuman Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain.
Marina BermishevaInstitute of Biochemistry and Genetics, Ufa Science Center, Russian Academy of Sciences, Ufa, Russian Federation.
Marcus Q BernardiniDivision of Gynecologic Oncology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada.
Michael J BirrerDepartment of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Line BjorgeDepartment of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.
Amanda BlackDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Kenneth BlanksteinClinical Cancer Genetics for the City of Hope, Clinical Cancer Genetics Community Research Network, Duarte, California, USA.
Marinus J BlokDepartment of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands.
Clara BodelonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Natalia BogdanovaRadiation Oncology Research Unit, Hannover Medical School, Hannover, Germany.
Anders BojesenDepartment of Clinical Genetics, Vejle Hospital, Vejle, Denmark.
Bernardo BonanniDivision of Cancer Prevention and Genetics, Istituto Europeo di Oncologia (IEO), Milan, Italy.
Åke BorgDepartment of Oncology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.
Angela R BradburyDepartment of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
James D BrentonCancer Research UK (CRUK) Cambridge Institute, University of Cambridge, Cambridge, UK.
Carole BrewerDepartment of Clinical Genetics, Royal Devon and Exeter Hospital, Exeter, UK.
Louise BrintonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Per BrobergDepartment of Cancer Epidemiology, University Hospital, Lund, Lund University, Lund, Sweden.
Angela Brooks-WilsonCanada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.
Fiona BruinsmaCancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia.
Joan BrunetGenetic Counseling Unit, Hereditary Cancer Program, IDIBGI (Institut d'Investigació Biomèdica de Girona), Catalan Institute of Oncology, Girona, Spain.
Bruno BuecherService de Génétique Oncologique, Institut Curie, Paris, France.
Ralf ButzowDepartment of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Saundra S BuysDepartment of Medicine, Huntsman Cancer Institute, Salt Lake City, Utah, USA.
Trinidad CaldesMolecular Oncology Laboratory, Hospital Clínico San Carlos, IdISSC (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Madrid, Spain.
Maria A CaligoSection of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa, Pisa, Italy.
Ian CampbellCancer Genetics Laboratory, Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Rikki CanniotoCancer Pathology and Prevention, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York, USA.
Michael E CarneyDepartment of Obstetrics and Gynecology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA.
Terence CesconClinical Cancer Genetics for the City of Hope, Clinical Cancer Genetics Community Research Network, Duarte, California, USA.
Salina B ChanCancer Risk Program, University of California, San Francisco, San Francisco, California, USA.
Jenny Chang-ClaudeDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Stephen ChanockDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Xiao Qing ChenDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Yoke-Eng ChiewCentre for Cancer Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.
Jocelyne ChiquetteUnité de Recherche en Santé des Populations, Centre des Maladies du Sein Deschênes-Fabia, Centre de Recherche FRSQ du Centre Hospitalier Affilié Universitaire de Québec, Quebec City, Quebec, Canada.
Wendy K ChungDepartments of Pediatrics and Medicine, Columbia University, New York, New York, USA.
Kathleen B M ClaesCenter for Medical Genetics, Ghent University, Ghent, Belgium.
Thomas ConnerDepartment of Medicine, Huntsman Cancer Institute, Salt Lake City, Utah, USA.
Linda S CookDivision of Epidemiology, Biostatistics and Preventative Medicine, Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
Jackie CookSheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, UK.
Daniel W CramerObstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Julie M CunninghamDivision of Experimental Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Aimee A D'AloisioSocial &Scientific Systems, Inc., Durham, North Carolina, USA.
Mary B DalyDepartment of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
Francesca DamiolaBâtiment Cheney D, Centre Léon Bérard, Lyon, France.
Sakaeva Dina DamirovnaDepartment of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russian Federation.
Agnieszka Dansonka-MieszkowskaDepartment of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.
Fanny DaoGynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Rosemarie DavidsonDepartment of Clinical Genetics, South Glasgow University Hospitals, Glasgow, UK.
Anna DeFazioCentre for Cancer Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.
Capucine DelnatteUnité d'Oncogénétique, ICO-Centre René Gauducheau, Nantes, France.
Kimberly F DohenyCenter for Inherited Disease Research, Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Orland DiezOncogenetics Group, Vall d'Hebron Institute of Oncology, Barcelona, Spain.
Yuan Chun DingDepartment of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA.
Jennifer Anne DohertyDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Susan M DomchekDepartment of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Cecilia M DorflingCancer Genetics Laboratory, Department of Genetics, University of Pretoria, Pretoria, South Africa.
Thilo DörkGynaecology Research Unit, Hannover Medical School, Hannover, Germany.
Laure DossusNutrition and Metabolism Section, International Agency for Research on Cancer (IARC-WHO), Lyon, France.
Mercedes DuranInstitute of Biology and Molecular Genetics, Universidad de Valladolid (IBGM-UVA), Valladolid, Spain.
Matthias DürstDepartment of Gynecology, Jena University Hospital-Friedrich Schiller University, Jena, Germany.
Bernd DworniczakInstitute of Human Genetics, Münster, Germany.
Diana EcclesUniversity of Southampton Faculty of Medicine, Southampton University Hospitals NHS Trust, Southampton, UK.
Todd EdwardsDivision of Epidemiology, Department of Medicine, Vanderbilt School of Medicine, Nashville, Tennessee, USA.
Ros EelesOncogenetics Team, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK.
Ursula EilberDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Bent EjlertsenDepartment of Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Arif B EkiciInstitute of Human Genetics, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany.
Steve EllisCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Mingajeva ElviraDepartment of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russian Federation.
EMBRACE Study
Kevin H EngDepartment of Biostatistics and Bioinformatics, Roswell Park Institute, Buffalo, New York, USA.
Christoph EngelInstitute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.
D Gareth EvansGenomic Medicine, Manchester Academic Health Sciences Centre, University of Manchester, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
Peter A FaschingDepartment of Gynecology and Obstetrics, Universtiy Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-Nuremberg, Erlangen, Germany.
Sarah FergusonDivision of Gynecologic Oncology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada.
Sandra Fert FerrerLaboratoire de Génétique Chromosomique, Hôtel Dieu Centre Hospitalier, Chambéry, France.
James M FlanaganDepartment of Surgery and Cancer, Imperial College London, London, UK.
Zachary C FogartyDivision of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, Rochester, Minnesota, USA.
Renée T FortnerDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Florentia FostiraMolecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, Athens, Greece.
William D FoulkesProgram in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montreal, Quebec, Canada.
George FountzilasDepartment of Medical Oncology, Papageorgiou, Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece.
Brooke L FridleyBiostatistics and Informatics Shared Resource, University of Kansas Medical Center, Kansas City, Kansas, USA.
Tara M FriebelHarvard T.H. Chan School of Public Health and Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Eitan FriedmanSusanne Levy Gertner Oncogenetics Unit, Institute of Human Genetics, Chaim Sheba Medical Center, Ramat Gan, Israel.
Debra FrostCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Patricia A GanzDivision of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center, UCLA Schools of Medicine and Public Health, Los Angeles, California, USA.
Judy GarberCancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
María J GarcíaHuman Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain.
Vanesa Garcia-BarberanMolecular Oncology Laboratory, Hospital Clínico San Carlos, IdISSC (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Madrid, Spain.
Andrea GehrigCentre of Familial Breast and Ovarian Cancer, Department of Medical Genetics, Institute of Human Genetics, University Würzburg, Würzburg, Germany.
GEMO Study Collaborators
Aleksandra Gentry-MaharajWomen's Cancer, Institute for Women's Health, University College London, London, UK.
Anne-Marie GerdesDepartment of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Graham G GilesCancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia.
Rosalind GlasspoolBeatson West of Scotland Cancer Centre, Glasgow, UK.
Gord GlendonOntario Cancer Genetics Network: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
Andrew K GodwinDepartment of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA.
David E GoldgarDepartment of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Teodora GoranovaCancer Research UK (CRUK) Cambridge Institute, University of Cambridge, Cambridge, UK.
Martin GoreDepartment of Medicine, Royal Marsden Hospital, London, UK.
Mark H GreeneClinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA.
Jacek GronwaldDepartment of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Stephen GruberKeck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA.
Eric HahnenCenter for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Cologne, Germany.
Christopher A HaimanDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA.
Niclas HåkanssonDivision of Nutritional Epidemiology, Department of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Ute HamannMolecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
Thomas V O HansenCenter for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Patricia A HarringtonDepartment of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
Holly R HarrisDivision of Nutritional Epidemiology, Department of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Jan HaukeCenter for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Cologne, Germany.
HEBON Study
Alexander HeinDepartment of Gynecology and Obstetrics, Universtiy Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-Nuremberg, Erlangen, Germany.
Alex HendersonInstitute of Genetic Medicine, Centre for Life, Newcastle-upon-Tyne Hospitals NHS Trust, Newcastle-upon-Tyne, UK.
Michelle A T HildebrandtDepartment of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Peter HillemannsClinics of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany.
Shirley HodgsonMedical Genetics Unit, St George's University of London, London, UK.
Claus K HøgdallDepartment of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Estrid HøgdallDepartment of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.
Frans B L HogervorstFamily Cancer Clinic, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Helene HollandDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Maartje J HooningDepartment of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, the Netherlands.
Karen HoskingDepartment of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
Ruea-Yea HuangCenter for Immunotherapy, Roswell Park Cancer Institute, Buffalo, New York, USA.
Peter J HulickCenter for Medical Genetics, NorthShore University HealthSystem, University of Chicago Pritzker School of Medicine, Evanston, Illinois, USA.
Jillian HungCentre for Cancer Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.
David J HunterProgram in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
David G HuntsmanDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Tomasz HuzarskiDepartment of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Evgeny N ImyanitovN.N. Petrov Institute of Oncology, St. Petersburg, Russian Federation.
Claudine IsaacsLombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.
Edwin S IversenDepartment of Statistical Science, Duke University, Durham, North Carolina, USA.
Louise IzattClinical Genetics, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Angel IzquierdoGenetic Counseling Unit, Hereditary Cancer Program, IDIBGI (Institut d'Investigació Biomèdica de Girona), Catalan Institute of Oncology, Girona, Spain.
Anna JakubowskaDepartment of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Paul JamesFamilial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Ramunas JanaviciusDepartment of Molecular and Regenerative Medicine, Hematology, Oncology and Transfusion Medicine Center, Vilnius University Hospital Santariskiu Clinics, Vilnius, Lithuania.
Mats JernetzDepartment of Obstetrics and Gynecology, Lund University Hospital, Lund, Sweden.
Allan JensenDepartment of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.
Uffe Birk JensenDepartment of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark.
Esther M JohnDepartment of Epidemiology, Cancer Prevention Institute of California, Fremont, California, USA.
Sharon JohnattyDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Michael E JonesDivision of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Päivi KannistoDepartment of Obstetrics and Gynecology, Lund University Hospital, Lund, Sweden.
Beth Y KarlanWomen's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Anthony KarnezisDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Karin KastDepartment of Gynaecology and Obstetrics, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
KConFab Investigators
Catherine J KennedyCentre for Cancer Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.
Elza KhusnutdinovaInstitute of Biochemistry and Genetics, Ufa Science Center, Russian Academy of Sciences, Ufa, Russian Federation.
Lambertus A KiemeneyRadboud University Medical Center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, the Netherlands.
Johanna I KiiskiDepartment of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.
Sung-Won KimDepartment of Surgery, Breast Care Center, Daerim St. Mary's Hospital, Seoul, Republic of Korea.
Susanne K KjaerDepartment of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Martin KöbelDepartment of Pathology, University of Calgary, Calgary, Alberta, Canada.
Reidun K KopperudDepartment of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.
Torben A KruseDepartment of Clinical Genetics, Odense University Hospital, Odense, Denmark.
Jolanta KupryjanczykDepartment of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.
Ava KwongHong Kong Hereditary Breast Cancer Family Registry, Hong Kong.
Yael LaitmanSusanne Levy Gertner Oncogenetics Unit, Institute of Human Genetics, Chaim Sheba Medical Center, Ramat Gan, Israel.
Diether LambrechtsVesalius Research Center, VIB, Leuven, Belgium.
Nerea LarrañagaPublic Health Division of Gipuzkoa, Regional Government of the Basque Country, Donostia-San Sebastian, Spain.
Melissa C LarsonDivision of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, Rochester, Minnesota, USA.
Conxi LazaroMolecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain.
Nhu D LeCancer Control Research, BC Cancer Agency, Vancouver, British Columbia, Canada.
Loic Le MarchandCancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA.
Jong Won LeeDepartment of Surgery, Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea.
Shashikant B LeleDepartment of Gynecological Oncology, Roswell Park Cancer Institute, Buffalo, New York, USA.
Arto LeminenDepartment of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.
Dominique LerouxDépartement de Génétique, Centre Hospitalier Universitaire de Grenoble, Grenoble, France.
Jenny LesterWomen's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Fabienne LesueurInstitut Curie, PSL Research Unviersity and INSERM U900, Paris, France.
Douglas A LevineGynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Dong LiangCollege of Pharmacy and Health Sciences, Texas Southern University, Houston, Texas, USA.
Clemens LiebrichCancer Center Wolfsburg, Clinics of Gynaecology, Wolfsburg, Germany.
Jenna LilyquistDepartment of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, Minnesota, USA.
Loren LipworthDivision of Epidemiology, Department of Medicine, Vanderbilt School of Medicine, Nashville, Tennessee, USA.
Jolanta LissowskaDepartment of Cancer Epidemiology and Prevention, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.
Karen H LuDepartment of Gynecologic Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Jan LubinńskiDepartment of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Craig LuccariniDepartment of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
Lene LundvallJuliane Marie Centre, Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Phuong L MaiClinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA.
Gustavo Mendoza-FandiñoDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA.
Siranoush ManoukianUnit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), Milan, Italy.
Leon F A G MassugerRadboud University Medical Center, Radboud Institute for Health Sciences, Department for Health Evidence, Nijmegen, the Netherlands.
Taymaa MayDivision of Gynecologic Oncology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada.
Sylvie MazoyerINSERM U1052, CNRS UMR 5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Centre Léon Bérard, Lyon, France.
Jessica N McAlpineOvarian Cancer Research (OVCARE) Program-Gynecologic Tissue Bank, Vancouver General Hospital and BC Cancer Agency, Vancouver, British Columbia, Canada.
Valerie McGuireDepartment of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California, USA.
John R McLaughlinPublic Health Ontario, Toronto, Ontario, Canada.
Iain McNeishInstitute of Cancer Sciences, University of Glasgow, Wolfson Wohl Cancer Research Centre, Beatson Institute for Cancer Research, Glasgow, UK.
Hanne Meijers-HeijboerDepartment of Clinical Genetics, VU University Medical Centre, Amsterdam, the Netherlands.
Alfons MeindlDepartment of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
Usha MenonWomen's Cancer, Institute for Women's Health, University College London, London, UK.
Arjen R MensenkampDepartment of Human Genetics, Radboud University Medical Centre, Nijmegen, the Netherlands.
Melissa A MerrittDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Roger L MilneCancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia.
Gillian MitchellFamilial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Francesmary ModugnoDivision of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Joanna Moes-SosnowskaDepartment of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.
Melissa MoffittKnight Cancer Institute, Oregon Health &Science University, Portland, Oregon, USA.
Marco MontagnaImmunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Kirsten B MoysichCancer Pathology and Prevention, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York, USA.
Anna Marie MulliganDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Jacob MusinskyClinical Genetics Research Laboratory, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Katherine L NathansonDepartment of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Lotte NedergaardDepartment of Pathology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Roberta B NessUniversity of Texas School of Public Health, Houston, Texas, USA.
Susan L NeuhausenDepartment of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, USA.
Heli NevanlinnaDepartment of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.
Dieter NiederacherDepartment of Gynaecology and Obstetrics, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Robert L NussbaumInvitae Corporation, San Francisco, California, USA.
Kunle OdunsiDepartment of Gynecological Oncology, Roswell Park Cancer Institute, Buffalo, New York, USA.
Edith OlahDepartment of Molecular Genetics, National Institute of Oncology, Budapest, Hungary.
Olufunmilayo I OlopadeCenter for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, Illinois, USA.
Håkan OlssonDepartment of Cancer Epidemiology, University Hospital, Lund, Lund University, Lund, Sweden.
Curtis OlswoldDepartment of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, Minnesota, USA.
David M O'MalleyDepartment of Obstetrics and Gynecology, Ohio State University and the James Cancer Center, Columbus, Ohio, USA.
Kai-Ren OngWest Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham, UK.
N Charlotte Onland-MoretJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
OPAL study group
Nicholas OrrBreast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, UK.
Sandra OrsulicWomen's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Ana OsorioHuman Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain.
Domenico PalliMolecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute-ISPO, Florence, Italy.
Laura PapiUnit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence, Italy.
Tjoung-Won Park-SimonClinics of Obstetrics and Gynaecology, Hannover Medical School, Hannover, Germany.
James PaulCancer Research UK Clinical Trials Unit, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
Celeste L PearceDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA.
Inge Søkilde PedersenSection of Molecular Diagnostics, Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark.
Petra H M PeetersJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
Bernard PeisselUnit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), Milan, Italy.
Ana PeixotoDepartment of Genetics, Portuguese Oncology Institute, Porto, Portugal.
Tanja PejovicKnight Cancer Institute, Oregon Health &Science University, Portland, Oregon, USA.
Liisa M PelttariDepartment of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.
Jennifer B PermuthDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA.
Paolo PeterlongoIFOM, FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology, Milan, Italy.
Lidia PezzaniUnit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), Milan, Italy.
Georg PfeilerDepartment of Obstetrics and Gynecology, Medical University of Vienna and Comprehensive Cancer Center, Vienna, Austria.
Kelly-Anne PhillipsCentre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.
Marion PiedmonteNRG Oncology, Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, New York, USA.
Malcolm C PikeDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA.
Anna M PiskorzCancer Research UK (CRUK) Cambridge Institute, University of Cambridge, Cambridge, UK.
Samantha R PobleteDepartment of Gynecological Oncology, Roswell Park Cancer Institute, Buffalo, New York, USA.
Timea PoczaDepartment of Molecular Genetics, National Institute of Oncology, Budapest, Hungary.
Elizabeth M PooleChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Bruce PoppeCenter for Medical Genetics, Ghent University, Ghent, Belgium.
Mary E PorteousSouth East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, UK.
Fabienne PrieurService de Génétique Clinique Chromosomique et Moléculaire, Centre Hospitalier Universitaire de St Etienne, St Etienne, France.
Darya ProkofyevaDepartment of Genetics and Fundamental Medicine, Bashkir State University, Ufa, Russian Federation.
Elizabeth PughCenter for Inherited Disease Research, Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Miquel Angel PujanaTranslational Research Laboratory, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, Barcelona, Spain.
Pascal PujolUnité d'Oncogénétique, Centre Hospitalier Universitaire Arnaud de Villeneuve, Montpellier, France.
Paolo RadiceUnit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale Tumori (INT), Milan, Italy.
Johanna RantalaDepartment of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden.
Christine Rappaport-FuerhauserDepartment of Obstetrics and Gynecology, Medical University of Vienna and Comprehensive Cancer Center, Vienna, Austria.
Gad RennertClalit National Israeli Cancer Control Center, Haifa, Israel.
Kerstin RhiemCenter for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Cologne, Germany.
Patricia RiceClinical Cancer Genetics for the City of Hope, Clinical Cancer Genetics Community Research Network, Duarte, California, USA.
Andrea RichardsonDepartment of Pathology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Mark RobsonClinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Gustavo C RodriguezDivision of Gynecologic Oncology, NorthShore University HealthSystem, University of Chicago, Evanston, Illinois, USA.
Cristina Rodríguez-AntonaBiomedical Network on Rare Diseases (CIBERER), Madrid, Spain.
Jane RommCenter for Inherited Disease Research, Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Matti A RookusDepartment of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Mary Anne RossingProgram in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Joseph H RothsteinDepartment of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California, USA.
Anja RudolphDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Ingo B RunnebaumDepartment of Gynecology, Jena University Hospital-Friedrich Schiller University, Jena, Germany.
Helga B SalvesenDepartment of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.
Dale P SandlerEpidemiology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA.
Minouk J SchoemakerDivision of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Leigha SenterClinical Cancer Genetics Program, Division of Human Genetics, Department of Internal Medicine, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA.
V Wendy SetiawanDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA.
Gianluca SeveriFacultés de Médecin, Université Paris-Sud, Villejuif, France.
Priyanka SharmaDepartment of Hematology and Oncology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Tameka ShelfordCenter for Inherited Disease Research, Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Nadeem SiddiquiDepartment of Gynaecological Oncology, Glasgow Royal Infirmary, Glasgow, UK.
Lucy E SideNorth East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London, UK.
Weiva SiehDepartment of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California, USA.
Christian F SingerDepartment of Obstetrics and Gynecology, Medical University of Vienna and Comprehensive Cancer Center, Vienna, Austria.
Hagay SobolDépartement Oncologie Génétique, Institut Paoli-Calmettes, Marseille, France.
Honglin SongDepartment of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
Melissa C SoutheyGenetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Victoria, Australia.
Amanda B SpurdleDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Zsofia StadlerClinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Doris SteinemannInstitute of Human Genetics, Hannover Medical School, Hannover, Germany.
Dominique Stoppa-LyonnetService de Génétique Oncologique, Institut Curie, Paris, France.
Lara E Sucheston-CampbellDepartment of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York, USA.
Grzegorz SukiennickiDepartment of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
Rebecca SutphenEpidemiology Center, College of Medicine, University of South Florida, Tampa, Florida, USA.
Christian SutterInstitute of Human Genetics, Department of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany.
Anthony J SwerdlowDivision of Genetics and Epidemiology, Institute of Cancer Research, London, UK.
Csilla I SzaboNational Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA.
Lukasz SzafronDepartment of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.
Yen Y TanDepartment of Obstetrics and Gynecology, Medical University of Vienna and Comprehensive Cancer Center, Vienna, Austria.
Jack A TaylorEpidemiology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA.
Muy-Kheng TeaDepartment of Obstetrics and Gynecology, Medical University of Vienna and Comprehensive Cancer Center, Vienna, Austria.
Manuel R TeixeiraDepartment of Genetics, Portuguese Oncology Institute, Porto, Portugal.
Soo-Hwang TeoCancer Research Initiatives Foundation, Sime Darby Medical Centre, Subang Jaya, Malaysia.
Kathryn L TerryObstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Pamela J ThompsonCancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Liv Cecilie Vestrheim ThomsenDepartment of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.
Darcy L ThullMagee-Womens Hospital of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Laima TihomirovaLatvian Biomedical Research and Study Centre, Riga, Latvia.
Anna V TinkerOvarian Cancer Research (OVCARE) Program-Cheryl Brown Ovarian Cancer Outcomes Unit (CBOCOU), BC Cancer Agency, Vancouver, British Columbia, Canada.
Marc TischkowitzProgram in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montreal, Quebec, Canada.
Silvia TognazzoImmunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Amanda Ewart TolandDivision of Human Cancer Genetics, Departments of Internal Medicine and Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, Ohio State University, Columbus, Ohio, USA.
Alicia ToneDivision of Gynecologic Oncology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada.
Britton TrabertDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Ruth C TravisCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Antonia TrichopoulouHellenic Health Foundation, Athens, Greece.
Nadine TungDepartment of Medical Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Shelley S TworogerChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Anne M van AltenaDivision of Gynecologic Oncology, Department of Obstetrics and Gynaecology, Radboud University Medical Centre, Nijmegen, the Netherlands.
David Van Den BergDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA.
Annemarie H van der HoutDepartment of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Rob B van der LuijtDepartment of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands.
Mattias Van HeetveldeCenter for Medical Genetics, Ghent University, Ghent, Belgium.
Els Van NieuwenhuysenDivision of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.
Elizabeth J van RensburgCancer Genetics Laboratory, Department of Genetics, University of Pretoria, Pretoria, South Africa.
Adriaan VandersticheleDivision of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.
Raymonda Varon-MateevaInstitute of Medical and Human Genetics, Charité Universitätsmedizin, Campus Virchov Klinikum, Berlin, Germany.
Ana VegaFundación Pública Galega de Medicina Xenómica, Servizo Galego de Saúde (SERGAS), Instituto de Investigación Sanitaria (IDIS), Santiago de Compostela, Spain.
Digna Velez EdwardsVanderbilt Epidemiology Center, Department of Medicine, Vanderbilt Medical School, Nashville, Tennessee, USA.
Ignace VergoteDivision of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.
Robert A VierkantDivision of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, Rochester, Minnesota, USA.
Joseph VijaiClinical Genetics Research Laboratory, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Athanassios VratimosMolecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, Athens, Greece.
Lisa WalkerOxford Regional Genetics Service, Churchill Hospital, Oxford, UK.
Christine WalshWomen's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Dorothea WandInstitute of Human Genetics, University Hospital, Leipzig, Germany.
Shan Wang-GohrkeDepartment of Obstetrics and Gynecology, University of Ulm, Ulm, Germany.
Barbara WappenschmidtCenter for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Cologne, Germany.
Penelope M WebbPopulation Health Department, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
Clarice R WeinbergBiostatistics and Computational Biology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle Park, North Carolina, USA.
Jeffrey N WeitzelClinical Cancer Genetics, City of Hope, Duarte, California, USA.
Nicolas WentzensenDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Alice S WhittemoreDepartment of Health Research and Policy-Epidemiology, Stanford University School of Medicine, Stanford, California, USA.
Juul T WijnenDepartments of Human Genetics and Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands.
Lynne R WilkensCancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA.
Alicja WolkDivision of Nutritional Epidemiology, Department of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Michelle WooDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Xifeng WuDepartment of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Anna H WuDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA.
Hannah YangDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Drakoulis YannoukakosMolecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, Athens, Greece.
Argyrios ZiogasDepartment of Epidemiology, University of California-Irvine, Irvine, California, USA.
Kristin K ZornMagee-Womens Hospital of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Steven A NarodWomen's College Research Institute, University of Toronto, Toronto, Ontario, Canada.
Douglas F EastonCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
Christopher I AmosCenter for Genomic Medicine, Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.
Joellen M SchildkrautDepartment of Public Health Sciences, University of Virginia, Charlottesville, Virginia, USA.
Susan J RamusSchool of Women's and Children's Health, Lowy Cancer Research Centre, University of New South Wales, Sydney, New South Wales, Australia.
Laura OttiniDepartment of Molecular Medicine, University La Sapienza, Rome, Italy.
Marc T GoodmanCancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Sue K ParkDepartment of Preventive Medicine, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Linda E KelemenDepartment of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.
Harvey A RischDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA.
Mads ThomassenDepartment of Clinical Genetics, Odense University Hospital, Odense, Denmark.
Kenneth OffitClinical Genetics Research Laboratory, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Jacques SimardGenomics Center, Centre Hospitalier Universitaire de Québec Research Center and Laval University, Quebec City, Quebec, Canada.
Rita Katharina SchmutzlerCenter for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO) and Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Cologne, Germany.
Dennis HazelettDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Alvaro N MonteiroDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA.
Fergus J CouchDivision of Experimental Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Andrew BerchuckDepartment of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA.
Georgia Chenevix-TrenchDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Ellen L GoodeDepartment of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, Minnesota, USA.
Thomas A SellersDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, USA.
Simon A GaytherCenter for Bioinformatics and Functional Genomics, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Antonis C AntoniouCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
Paul D P PharoahCentre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.ORCID http://orcid.org/0000-0001-8494-732X
University of Cambridge · GBRoswell Park Comprehensive Cancer Center · USCedars-Sinai Medical Center · USUniversity of Southern California · USMemorial Sloan Kettering Cancer Center · USBC Cancer Agency · CABrigham and Women's Hospital · USJohns Hopkins University · USUniversity of Copenhagen · DKInstitute of Cancer Research · GBLund University · SEMedizinische Hochschule Hannover · DEMayo Clinic in Florida · USNational Institutes of Health · USRadboud University Nijmegen · NLThe University of Texas MD Anderson Cancer Center · USUniversity of Helsinki · FIGerman Cancer Research Center · DEQIMR Berghofer Medical Research Institute · AUThe University of Melbourne · AU

Funding

NRG Oncology Network Group Operations Center - GY9 BIQSFP Reports/BudgetsU10CA180868 · NCI · NRG ONCOLOGY FOUNDATION, INC. · PI NORMAN WOLMARK · 2014 to 2026
$206.8M
Statistics CoreU10CA180822 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Elaina Harper · 2014 to 2026
$146.4M
NRG Oncology NCORP Research Base-BIQSFPUG1CA189867 · NCI · NRG ONCOLOGY FOUNDATION, INC. · PI Deborah Watkins Bruner, Lisa A. Kachnic · 2014 to 2026
$140.5M
WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Dietmar J Kappes · 1985 to 2026
$138.8M
Clinical Genetic Studies of Familial and Hereditary Cancer SyndromesZIACP010144 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI SAVAGE, SHARON A. · 2009 to 2025
$111.8M
TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI Louis M Weiner · 1990 to 2026
$71.5M
University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI GERTRAUD MASKARINEC · 1996 to 2026
$56.2M
Translational Science Laboratory Shared ResourceP30CA138313 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Jian Ouyang · 2009 to 2026
$42.7M
Use of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancerP50CA136393 · NCI · MAYO CLINIC ROCHESTER · PI ELLEN L. GOODE · 2009 to 2026
$37.0M
Environmental and Genetic Risk Factors For Breast Cancer: The Sister StudyZIAES044005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 2009 to 2025
$22.7M
Cancer Research UK 10124Cancer Research UK 11174Cancer Research UK 15973Cancer Research UK 16491Cancer Research UK 16561Cancer Research UK 20861Cancer Research UK 23382Medical Research Council G0601891NCI NIH HHS P30 CA006927NCI NIH HHS P30 CA023108NCI NIH HHS P30 CA051008NCI NIH HHS P30 CA071789NCI NIH HHS P30 CA076292NCI NIH HHS P30 CA138313NCI NIH HHS P50 CA136393NCI NIH HHS R01 CA058598NCI NIH HHS R01 CA149429NCI NIH HHS R01 CA176785NCI NIH HHS R01 CA204954NCI NIH HHS R01 CA211707NCI NIH HHS R25 CA092049NCI NIH HHS U10 CA180822NCI NIH HHS U10 CA180868NCI NIH HHS U19 CA148112NCI NIH HHS UG1 CA189867World Health Organization 001
6 · The paper itself

Abstract

To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC cases and 40,941 controls. We identified nine new susceptibility loci for different EOC histotypes: six for serous EOC histotypes (3q28, 4q32.3, 8q21.11, 10q24.33, 18q11.2 and 22q12.1), two for mucinous EOC (3q22.3 and 9q31.1) and one for endometrioid EOC (5q12.3). We then performed meta-analysis on the results for high-grade serous ovarian cancer with the results from analysis of 31,448 BRCA1 and BRCA2 mutation carriers, including 3,887 mutation carriers with EOC. This identified three additional susceptibility loci at 2q13, 8q24.1 and 12q24.31. Integrated analyses of genes and regulatory biofeatures at each locus predicted candidate susceptibility genes, including OBFC1, a new candidate susceptibility gene for low-grade and borderline serous EOC.

Indexed as

AllelesBRCA1 ProteinBRCA2 ProteinCarcinoma, Ovarian EpithelialFemaleGenetic LociGenetic Predisposition to DiseaseGenome-Wide Association StudyGenotypeHumansMeta-Analysis as TopicMutationNeoplasms, Glandular and EpithelialOvarian NeoplasmsPolymorphism, Single NucleotideRisk FactorsBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinBRCA2 protein, humanStn1 protein, humanTelomere-Binding Proteins

Identifiers

PMID28346442
PMCPMC5612337
OpenAlexW2601822003

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.