Evidence map›Paper›PMID 28345776›Full record

ArticleJournal of clinical laboratory analysis2018

Red blood cell distribution width and neutrophil to lymphocyte ratio are correlated with disease activity of dermatomyositis and polymyositis.

Ming-Zhu Gao, Yuan-Lan Huang, Xiao-Dan Wu, Qiang-Wei Xu, Rong Ji, Bing Gu, Ai-Yan Zhang, Ting-Ting Hao, Zhi-Jun Han, Tian-Li Ren

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ming-Zhu GaoDepartment of Laboratory Medicine, Wuxi Second People's Hospital of Nanjing Medical University, Wuxi, China.ORCID http://orcid.org/0000-0002-8556-1792
Yuan-Lan HuangDepartment of Laboratory Medicine, No.455 Hospital of the Chinese People's Liberation Army, Shanghai, China.
Xiao-Dan WuDepartment of Laboratory Medicine, Wuxi Second People's Hospital of Nanjing Medical University, Wuxi, China.
Qiang-Wei XuDepartment of Rheumatology, Wuxi Second People's Hospital of Nanjing Medical University, Wuxi, China.
Rong JiDepartment of Rheumatology, Wuxi Second People's Hospital of Nanjing Medical University, Wuxi, China.
Bing GuDepartment of Laboratory Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Ai-Yan ZhangDepartment of Laboratory Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Ting-Ting HaoDepartment of Laboratory Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Zhi-Jun HanDepartment of Laboratory Medicine, Wuxi Second People's Hospital of Nanjing Medical University, Wuxi, China.
Tian-Li RenDepartment of Rheumatology, Wuxi Second People's Hospital of Nanjing Medical University, Wuxi, China.
Wuxi People's Hospital · CNXuzhou Medical College · CNChinese People 's Liberation Army No.455 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies indicated that both red blood cell distribution width (RDW) and neutrophil to lymphocyte ratio (NLR) were useful indices in assessing the disease activity of autoimmune diseases. However, the evidence for the association between RDW, NLR and dermatomyositis (DM) and polymyositis (PM) is limited. The aim of this study is to investigate the association between the disease activity of PM/DM and both RDW and NLR.

methodsMedical records of 114 PM/DM patients and 114 healthy controls were retrospectively reviewed, and their RDW, NLR and myositis disease activity assessment visual analogue scale (MYOACT) on admission were extracted. The correlations between RDW, NLR and MYOACT were analyzed using the Spearman approach and multivariable model.

resultsPM/DM patients had significantly higher RDW and NLR. Increased RDW in PM/DM patients was not completely attributed to decreased hemoglobin or therapeutic agents. Both RDW and NLR are independently and positively correlated MYOACT.

conclusionBoth RDW and NLR are useful indices in assessing the disease activity of PM/DM.

Indexed as

DermatomyositisPolymyositisAdultCase-Control StudiesErythrocyte IndicesFemaleHumansLeukocyte CountLymphocytesMaleMiddle AgedNeutrophilsdermatomyositisdisease activityneutrophil to lymphocyte ratiopolymyositisred blood cell distribution width

Identifiers

PMID28345776
PMCPMC6816967
OpenAlexW2603251362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.